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Title: Whole-Body Optical Imaging in Animal Models to Assess Cancer Development and Progression |
Year: 2007 |
Publication: Clinical Cancer Research |
Volume: 13 |
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Keywords: molecular imaging; cancer; reporter genes; animal models; clinical applications; noninvasive imaging in animal models; animal models of cancer |
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Author: Kenneth M Kozloff, Ralph Weissleder and Umar Mahmood |
Title: Noninvasive Optical Detection of Bone Mineral |
Year: 2007 |
Publication: Journal of Bone and Mineral Research |
Volume: 22 |
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Keywords: FMT; OsteoSense; ProSense bone mineralization; bone turnover markers; molecular imaging; bisphosphonates; in vivo imaging |
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Author: Farouc A. Jaffer, Dong-Eog Kim, Luisa Quinti, Ching-Hsuan Tung, Elena Aikawa, Ashvin N. Pande, Rainer H. Kohler, Guo-Ping Shi, Peter Libby and Ralph Weissleder |
Title: Optical Visualization of Cathepsin K Activity in Atherosclerosis With a Novel, Protease-Activatable Fluorescence Sensor |
Year: 2007 |
Publication: Circulation |
Volume: 115 |
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Keywords: in vivo imaging; atherosclerosis; cathepsin K; fluorescence; imaging; inflammation; AngioSense |
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Author: Elena Aikawa, Matthias Nahrendorf, David Sosnovik, Vincent M. Lok, Farouc A. Jaffer, Masanori Aikawa and Ralph Weissleder |
Title: Multimodality Molecular Imaging Identifies Proteolytic and Osteogenic Activities in Early Aortic Valve Disease |
Year: 2007 |
Publication: Circulation |
Volume: 115 |
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Keywords: valves; stenosis; inflammation; atherosclerosis; hypercholesterolemia; imaging; ProSense; OsteoSense |
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Author: Woods, Nicholas T; Yamaguchi, Hirohito; Lee, Francis Y; Bhalla, Kapil N; Wang, Hong-Gang |
Title: Anoikis, initiated by Mcl-1 degradation and Bim induction, is deregulated during oncogenesis |
Year: 2007 |
Publication: Cancer research |
Volume: 67 |
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Keywords: Animals; Anoikis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Bioware; Caspase 3; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Glycogen Synthase Kinase 3; Humans; L-Lactate Dehydrogenase; MDA-MB-231-D3H2LN cells; Membrane Proteins; Mice; Neoplasm Metastasis; Neoplasm Proteins; NIH 3T3 Cells; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2 |
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Author: Beckers, Annelies; Organe, Sophie; Timmermans, Leen; Scheys, Katryn; Peeters, Annelies; Brusselmans, Koen; Verhoeven, Guido; Swinnen, Johannes V |
Title: Chemical inhibition of acetyl-CoA carboxylase induces growth arrest and cytotoxicity selectively in cancer cells |
Year: 2007 |
Publication: Cancer research |
Volume: 67 |
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Keywords: Acetyl-CoA Carboxylase; Apoptosis; Autophagy; Bioware; Cell Death; Cell Proliferation; Drug Evaluation, Preclinical; Fatty Acids; Humans; Macrolides; Male; Neoplasms; Palmitic Acid; PC-3M-luc; Phospholipids; Prostatic Neoplasms; Tumor Cells, Cultured |
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Author: Bednar, Bohumil; Zhang, Guo-Jun; Williams Jr, David L; Hargreaves, Richard; Sur, Cyrille |
Title: Optical molecular imaging in drug discovery and clinical development |
Year: 2007 |
Publication: Expert Opinion on Drug Discovery |
Volume: 2 |
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Keywords: Bioware; PC-3M-luc |
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Author: Casarez, Eli V; Dunlap-Brown, Marya E; Conaway, Mark R; Amorino, George P |
Title: Radiosensitization and modulation of p44/42 mitogen-activated protein kinase by 2-Methoxyestradiol in prostate cancer models |
Year: 2007 |
Publication: Cancer research |
Volume: 67 |
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Keywords: Animals; Bioware; Carcinoma; Estradiol; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; PC-3M-luc; Phosphorylation; Prostatic Neoplasms; Radiation-Sensitizing Agents; Subcutaneous Tissue; Transplantation, Heterotopic; Tumor Cells, Cultured; Xenograft Model Antitumor Assays |
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Author: Figg, William D; Li, Haiqing; Sissung, Tristan; Retter, Avi; Wu, Shenhong; Gulley, James L; Arlen, Phil; Wright, John J; Parnes, Howard; Fedenko, Kathy; Latham, Lea; Steinberg, Seth M; Jones, Elizabeth; Chen, Clara; Dahut, William |
Title: Pre-clinical and clinical evaluation of estramustine, docetaxel and thalidomide combination in androgen-independent prostate cancer |
Year: 2007 |
Publication: BJU international |
Volume: 99 |
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Keywords: Aged; Androgens; Animals; Antineoplastic Combined Chemotherapy Protocols; Aryl Hydrocarbon Hydroxylases; Bioware; Cytochrome P-450 Enzyme System; Estramustine; Genotype; Humans; Male; Mice; Mice, Nude; Middle Aged; PC-3M-luc; Prostatic Neoplasms; Survival Analysis; Taxoids; Thalidomide; Treatment Outcome |
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Author: Giubellino, Alessio; Gao, Yang; Lee, Sunmin; Lee, Min-Jung; Vasselli, James R; Medepalli, Sampath; Trepel, Jane B; Burke, Terrence R, Jr; Bottaro, Donald P |
Title: Inhibition of tumor metastasis by a growth factor receptor bound protein 2 Src homology 2 domain-binding antagonist |
Year: 2007 |
Publication: Cancer research |
Volume: 67 |
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Keywords: Animals; Bioware; Cell Line, Tumor; Cell Movement; Cell Proliferation; Gene Expression Regulation, Neoplastic; GRB2 Adaptor Protein; Humans; Mice; Mice, SCID; Microscopy, Fluorescence; Neoplasm Metastasis; Neoplasm Transplantation; PC-3M-luc; Protein Binding; Protein Structure, Tertiary; Tetrazolium Salts; Thiazoles |
