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Author: Baoum, A.; Ovcharenko, D.; Berkland, C. |
Title: Calcium condensed cell penetrating peptide complexes offer highly efficient, low toxicity gene silencing |
Year: 2012 |
Publication: Int J Pharm |
Volume: 427 |
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Keywords: A549-luc-C8, A549-luc, IVIS, Bioware, Calcium/chemistry; Cell Line; Cell-Penetrating Peptides/administration & dosage/*chemistry; Drug Carriers/administration & dosage/adverse effects/*chemistry; *Gene Silencing; Genetic Therapy/*methods; Humans; Luciferases; Nanoparticles/administration & dosage/chemistry; RNA, Small Interfering/*administration & dosage/chemistry; Tissue Distribution |
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Author: Cerchia, L.; Esposito, C. L.; Camorani, S.; Rienzo, A.; Stasio, L.; Insabato, L.; Affuso, A.; de Franciscis, V. |
Title: Targeting Axl With an High-affinity Inhibitory Aptamer |
Year: 2012 |
Publication: Mol Ther |
Volume: 20 |
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Keywords: A549-luc-C8, A549-luc, IVIS, Bioware |
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Author: Cheng, H. H.; Kuo, C. C.; Yan, J. L.; Chen, H. L.; Lin, W. C.; Wang, K. H.; Tsai, K. K.; Guven, H.; Flaberg, E.; Szekely, L.; Klein, G.; Wu, K. K. |
Title: Control of cyclooxygenase-2 expression and tumorigenesis by endogenous 5-methoxytryptophan |
Year: 2012 |
Publication: Proc Natl Acad Sci U S A |
Volume: 109 |
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Keywords: A549-luc-C8, A549-luc, IVIS, Bioware, Acetylserotonin O-Methyltransferase/metabolism; Animals; Biocatalysis/drug effects; Cell Line, Tumor; Cell Movement/drug effects; Cell Proliferation/drug effects; Cell Transformation, Neoplastic/drug effects/*pathology; Cyclooxygenase 2/*metabolism; Cyclooxygenase 2 Inhibitors/pharmacology; Fibroblasts/drug effects/metabolism; Humans; Metabolic Networks and Pathways/drug effects; Metabolomics; Mice; Neoplasm Metastasis; Solubility/drug effects; Subcellular Fractions/drug effects/metabolism; Tryptophan/*analogs & derivatives/biosynthesis/metabolism/pharmacology; Tryptophan Hydroxylase/metabolism; Xenograft Model Antitumor Assays |
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Author: Comenge, J.; Sotelo, C.; Romero, F.; Gallego, O.; Barnadas, A.; Parada, T. G.; Dominguez, F.; Puntes, V. F. |
Title: Detoxifying antitumoral drugs via nanoconjugation: the case of gold nanoparticles and cisplatin |
Year: 2012 |
Publication: PLoS One |
Volume: 7 |
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Keywords: A549-luc-C8, A549-luc, IVIS, Bioware |
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Author: Hanai, J.; Doro, N.; Sasaki, A. T.; Kobayashi, S.; Cantley, L. C.; Seth, P.; Sukhatme, V. P. |
Title: Inhibition of lung cancer growth: ATP citrate lyase knockdown and statin treatment leads to dual blockade of mitogen-activated protein kinase (MAPK) and phosphatidylinositol-3-kinase (PI3K)/AKT pathways |
Year: 2012 |
Publication: J Cell Physiol |
Volume: 227 |
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Keywords: A549-luc-C8, A549-luc, IVIS, Bioware, ATP Citrate (pro-S)-Lyase/*antagonists & inhibitors/genetics; Animals; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Combined Modality Therapy; Epithelial-Mesenchymal Transition; Female; Gene Knockdown Techniques; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors/*therapeutic use; Lung Neoplasms/*drug therapy/enzymology/pathology/*therapy; MAP Kinase Signaling System/drug effects; Mice; Mutation; Phosphatidylinositol 3-Kinases/antagonists & inhibitors; Proto-Oncogene Proteins c-akt/antagonists & inhibitors; Receptor, Epidermal Growth Factor/genetics; Signal Transduction/drug effects; Xenograft Model Antitumor Assays |
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Author: Joh, E. H.; Hollenbaugh, J. A.; Kim, B.; Kim, D. H. |
Title: Pleckstrin homology domain of akt kinase: a proof of principle for highly specific and effective non-enzymatic anti-cancer target |
Year: 2012 |
Publication: PLoS One |
Volume: 7 |
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Keywords: A549-luc-C8, A549-luc, IVIS, Bioware |
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Author: Johnson, J. L.; Pillai, S.; Pernazza, D.; Sebti, S. M.; Lawrence, N. J.; Chellappan, S. P. |
Title: Regulation of matrix metalloproteinase genes by E2F transcription factors: Rb-Raf-1 interaction as a novel target for metastatic disease |
Year: 2012 |
Publication: Cancer Res |
Volume: 72 |
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Keywords: A549-luc-C8, A549-luc, IVIS, Bioware, Animals; Breast Neoplasms/genetics/metabolism/pathology; Carcinoma, Non-Small-Cell Lung/genetics/metabolism/pathology; Cell Line, Tumor; E2F Transcription Factors/*genetics/metabolism; Enzyme Assays/methods; Female; Gelatin/metabolism; *Gene Expression Regulation, Enzymologic; *Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms/genetics/metabolism/pathology; Matrix Metalloproteinases/biosynthesis/*genetics/metabolism; Mice; Mice, SCID; Neoplasm Metastasis; Phosphatidylethanolamine Binding Protein/*metabolism; Retinoblastoma Protein/genetics/*metabolism; Transcription, Genetic; Transfection |
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Author: Zhuang, H.; Jiang, W.; Zhang, X.; Qiu, F.; Gan, Z.; Cheng, W.; Zhang, J.; Guan, S.; Tang, B.; Huang, Q.; Wu, X.; Huang, X.; Hu, Q.; Lu, M.; Hua, Z. C. |
Title: Suppression of HSP70 expression sensitizes NSCLC cell lines to TRAIL-induced apoptosis by upregulating DR4 and DR5 and downregulating c-FLIP-L expressions |
Year: 2012 |
Publication: J Mol Med (Berl) |
Volume: |
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Keywords: A549-luc-C8, A549-luc, IVIS, Bioware |
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Author: Alsaadi, M.; Italia, J. L.; Mullen, A. B.; Ravi Kumar, M. N.; Candlish, A. A.; Williams, R. A.; Shaw, C. D.; Al Gawhari, F.; Coombs, G. H.; Wiese, M.; Thomson, A. H.; Puig-Sellart, M.; Wallace, J.; Sharp, A.; Wheeler, L.; Warn, P.; Carter, K. C. |
Title: The efficacy of aerosol treatment with non-ionic surfactant vesicles containing amphotericin B in rodent models of leishmaniasis and pulmonary aspergillosis infection |
Year: 2012 |
Publication: J Control Release |
Volume: 160 |
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Keywords: IVIS, B16-F10-luc-G5, B16F10-luc-G5, B16-F10-luc, B16F10-luc, Aerosols; Amphotericin B/*administration & dosage; Animals; Antifungal Agents/*administration & dosage; Cricetinae; Disease Models, Animal; Drug Carriers/*administration & dosage; Female; Firefly Luciferin/administration & dosage; Leishmaniasis/*drug therapy/metabolism/microbiology; Liver/metabolism/microbiology; Lung/metabolism/microbiology; Mesocricetus; Mice; Mice, Inbred BALB C; Pulmonary Aspergillosis/*drug therapy/metabolism/microbiology; Rats; Rats, Sprague-Dawley; Surface-Active Agents/*administration & dosage |
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Author: Carlisle, R.; Seymour, L. W.; Coussios, C. C. |
Title: Targeting of Liposomes via PSGL1 for Enhanced Tumor Accumulation |
Year: 2012 |
Publication: Pharm Res |
Volume: |
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Keywords: IVIS, B16-F10-luc-G5, B16F10-luc-G5, B16-F10-luc, B16F10-luc |
