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Author: Stan, Silvia D; Hahm, Eun-Ryeong; Warin, Renaud; Singh, Shivendra V |
Title: Withaferin A causes FOXO3a- and Bim-dependent apoptosis and inhibits growth of human breast cancer cells in vivo |
Year: 2008 |
Publication: Cancer research |
Volume: 68 |
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Keywords: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Bioware; Breast Neoplasms; Cell Growth Processes; Cell Line, Tumor; Ergosterol; Female; Forkhead Transcription Factors; Humans; MDA-MB-231-D3H1 cells; Membrane Proteins; Mice; Mice, Nude; Proto-Oncogene Proteins; RNA, Small Interfering; Transfection; Withanolides; Xenograft Model Antitumor Assays |
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Author: Inglefield, Jon R; Dumitru, Calin Dan; Alkan, Sefik S; Gibson, Sheila J; Lipson, Kenneth E; Tomai, Mark A; Larson, Chris J; Vasilakos, John P |
Title: TLR7 agonist 852A inhibition of tumor cell proliferation is dependent on plasmacytoid dendritic cells and type I IFN |
Year: 2008 |
Publication: Journal of interferon & cytokine research: the official journal of the International Society for Interferon and Cytokine Research |
Volume: 28 |
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Keywords: Aminoquinolines; Animals; B16-F10-luc-G5 cells; Bioware; Cell Line, Tumor; Cell Proliferation; Cell Survival; Culture Media, Conditioned; dendritic cells; Humans; Interferon Type I; Leukocytes, Mononuclear; Lung; Melanoma; Mice; Neoplasms; Oligodeoxyribonucleotides; Quinolines; Subcellular Fractions; Sulfonamides; Toll-Like Receptor 7 |
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Author: |
Title: Macrophage mannose receptor on lymphatics controls cell trafficking |
Year: 2008 |
Publication: Blood |
Volume: 112 |
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Keywords: Animals; Antigen Presentation; Antigens, Neoplasm; B16-F10-luc-G5 cells; Bioware; B-Lymphocytes; Cell Adhesion; Cell Line, Tumor; Cell Movement; dendritic cells; Female; Lectins, C-Type; Lymphatic Metastasis; Lymphatic System; Macrophages; Male; Mannose-Binding Lectins; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Cell Surface; T-Lymphocytes |
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Author: Smith, Eric L; Schuchman, Edward H |
Title: Acid sphingomyelinase overexpression enhances the antineoplastic effects of irradiation in vitro and in vivo |
Year: 2008 |
Publication: Molecular therapy: the journal of the American Society of Gene Therapy |
Volume: 16 |
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Keywords: Animals; Antineoplastic Agents; Autophagy; B16-F10-luc-G5 cells; Bioware; Cell Survival; Cells, Cultured; Ceramides; Cesium Radioisotopes; CHO Cells; Combined Modality Therapy; Cricetinae; Cricetulus; Endothelium, Vascular; Female; Gamma Rays; Gene Expression Regulation, Enzymologic; Gene Therapy; Humans; Melanoma, Experimental; Mice; Sphingomyelin Phosphodiesterase |
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Author: Xing, Yifei; Lu, Xiaochun; Pua, Eric C; Zhong, Pei |
Title: The effect of high intensity focused ultrasound treatment on metastases in a murine melanoma model |
Year: 2008 |
Publication: Biochemical and biophysical research communications |
Volume: 375 |
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Keywords: Animals; B16-F10-luc-G5 cells; Bioware; Cytotoxicity Tests, Immunologic; Female; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Ultrasonic Therapy |
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Author: Rambow-Larsen, Amy A; Rajashekara, Gireesh; Petersen, Erik; Splitter, Gary |
Title: Putative quorum-sensing regulator BlxR of Brucella melitensis regulates virulence factors including the type IV secretion system and flagella |
Year: 2008 |
Publication: Journal of bacteriology |
Volume: 190 |
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Keywords: Amino Acid Sequence; Animals; Bioware; Brucella melitensis; Brucellosis; Disease Models, Animal; Flagella; Gene Deletion; Gene Expression Regulation, Bacterial; Interferon Regulatory Factor-1; Macrophages; Mice; Mice, Mutant Strains; Molecular Sequence Data; Oligonucleotide Array Sequence Analysis; pXen-13; Quorum Sensing; Repressor Proteins; Trans-Activators; Virulence Factors |
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Author: Vuong, Cuong; Kocianova, Stanislava; Yu, Jun; Kadurugamuwa, Jagath L; Otto, Michael |
Title: Development of real-time in vivo imaging of device-related Staphylococcus epidermidis infection in mice and influence of animal immune status on susceptibility to infection |
Year: 2008 |
Publication: The Journal of infectious diseases |
Volume: 198 |
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Keywords: Animals; Biofilms; Bioware; Colony-Forming Units Assay; Disease Susceptibility; Female; Luminescence; Mice; Mice, SCID; pXen-5; Staphylococcal Infections; Staphylococcus epidermidis; T-Lymphocytes; T-Lymphocytes, Cytotoxic |
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Author: Kadurugamuwa, J. L.; Francis, K. P. |
Title: Bioluminescent imaging of bacterial biofilm infections in vivo |
Year: 2008 |
Publication: Methods in Molecular Biology |
Volume: 431 |
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Keywords: Bioware, Xen29, Animals, Bacteria/chemistry/ genetics, Bacterial Infections/diagnosis/ microbiology, Biofilms/ growth & development, Diagnostic Imaging/methods, Luminescent Measurements/ methods IVIS, Xenogen, Xen5, Xen44 |
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Author: Heit, Bryan; Robbins, Stephen M; Downey, Charlene M; Guan, Zhiwen; Colarusso, Pina; Miller, B Joan; Jirik, Frank R; Kubes, Paul |
Title: PTEN functions to 'prioritize' chemotactic cues and prevent 'distraction' in migrating neutrophils |
Year: 2008 |
Publication: Nature immunology |
Volume: 9 |
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Keywords: Animals; Arthritis, Experimental; Bioware; Chemotaxis, Leukocyte; Humans; Inflammation; Mice; Mice, Transgenic; Neutrophils; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Phosphates; Protein Transport; PTEN Phosphohydrolase; Xen29 |
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Author: |
Title: Quantitative mouse model of implant-associated osteomyelitis and the kinetics of microbial growth, osteolysis, and humoral immunity |
Year: 2008 |
Publication: Journal of orthopaedic research: official publication of the Orthopaedic Research Society |
Volume: 26 |
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Keywords: Animals; Antibody Formation; Bacterial Proteins; Bioware; Disease Models, Animal; DNA, Bacterial; Endonucleases; Female; Mice; Mice, Inbred C57BL; Micrococcal Nuclease; Osteolysis; Osteomyelitis; Prosthesis-Related Infections; Reverse Transcriptase Polymerase Chain Reaction; Staphylococcal Infections; Staphylococcus aureus; Tibia; Xen29 |