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Author: Earley, S.; Vinegoni, C.; Dunham, J.; Gorbatov, R.; Feruglio, P. F.; Weissleder, R. |
Title: In vivo imaging of drug-induced mitochondrial outer membrane permeabilization at single-cell resolution |
Year: 2012 |
Publication: Cancer Res |
Volume: 72 |
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Keywords: AngioSense, Annexin Vivo, Annexin-Vivo, Aniline Compounds/*pharmacology; Animals; Antineoplastic Agents/*pharmacology; *Apoptosis; Breast Neoplasms/drug therapy/*physiopathology; Cell Line, Tumor; Female; Green Fluorescent Proteins; Humans; Image Processing, Computer-Assisted; Mice; Mice, Nude; Mitochondrial Membranes/drug effects/*physiology; Mitochondrial Proteins/metabolism; Molecular Imaging/*methods; Pancreatic Neoplasms/drug therapy/*physiopathology; Proto-Oncogene Proteins c-bcl-2/antagonists & inhibitors; Recombinant Fusion Proteins/metabolism; Single-Cell Analysis; Sulfonamides/*pharmacology; Tumor Microenvironment |
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Author: Fu, A.; Wilson, R. J.; Smith, B. R.; Mullenix, J.; Earhart, C.; Akin, D.; Guccione, S.; Wang, S. X.; Gambhir, S. S. |
Title: Fluorescent magnetic nanoparticles for magnetically enhanced cancer imaging and targeting in living subjects |
Year: 2012 |
Publication: ACS Nano |
Volume: 6 |
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Keywords: AngioSense, Animals; Cell Line, Tumor; Fluorescent Dyes/*chemistry/*diagnostic use; Glioblastoma/*pathology; Humans; Magnetic Fields; Magnetite Nanoparticles/*diagnostic use; Materials Testing; Mice; Mice, SCID; Microscopy, Fluorescence/*methods; Nanocapsules/*chemistry/ultrastructure; Particle Size |
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Author: Kozlowski, C.; Weimer, R. M. |
Title: An automated method to quantify microglia morphology and application to monitor activation state longitudinally in vivo |
Year: 2012 |
Publication: PLoS One |
Volume: 7 |
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Keywords: AngioSense, Animals; Antigens, CD/metabolism; Antigens, Differentiation, Myelomonocytic/metabolism; Calcium-Binding Proteins/metabolism; Central Nervous System/metabolism; Green Fluorescent Proteins/genetics/*metabolism; Immunohistochemistry/*methods; Lipopolysaccharides/pharmacology; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microfilament Proteins/metabolism; Microglia/cytology/drug effects/*metabolism; Microscopy, Confocal/*methods; Receptors, Cytokine/genetics/metabolism; Receptors, HIV/genetics/metabolism; Reproducibility of Results |
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Author: Lee, S.; Vinegoni, C.; Feruglio, P. F.; Fexon, L.; Gorbatov, R.; Pivoravov, M.; Sbarbati, A.; Nahrendorf, M.; Weissleder, R. |
Title: Real-time in vivo imaging of the beating mouse heart at microscopic resolution |
Year: 2012 |
Publication: Nat Commun |
Volume: 3 |
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Keywords: AngioSense |
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Author: Matsumoto, K.; Azami, T.; Otsu, A.; Takase, H.; Ishitobi, H.; Tanaka, J.; Miwa, Y.; Takahashi, S.; Ema, M. |
Title: Study of normal and pathological blood vessel morphogenesis in Flt1-tdsRed BAC Tg mice |
Year: 2012 |
Publication: Genesis |
Volume: 50 |
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Keywords: AngioSense, Animals; Blood Vessels/embryology/*physiology; Chromosomes, Artificial, Bacterial; Embryo, Mammalian; Endothelial Cells/cytology/metabolism; Endothelium, Vascular/cytology/embryology/metabolism; Female; Founder Effect; Gene Expression Regulation, Developmental; Genes, Reporter; Mice; *Mice, Transgenic; Microscopy, Fluorescence; Morphogenesis/physiology; *Neovascularization, Pathologic; *Neovascularization, Physiologic; Retina/embryology/*physiology; Vascular Endothelial Growth Factor A/genetics/metabolism; Vascular Endothelial Growth Factor Receptor-1/genetics/*metabolism; Vascular Endothelial Growth Factor Receptor-2/genetics/metabolism |
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Author: Rao, S. M.; Auger, J. L.; Gaillard, P.; Weissleder, R.; Wada, E.; Torres, R.; Kojima, M.; Benoist, C.; Mathis, D.; Binstadt, B. A. |
Title: The neuropeptide neuromedin U promotes autoantibody-mediated arthritis |
Year: 2012 |
Publication: Arthritis Res Ther |
Volume: 14 |
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Keywords: AngioSense, Animals; Arthritis/genetics/*immunology/metabolism; Autoantibodies/*immunology; Bone Marrow Cells/immunology/metabolism/pathology; Calcium/immunology/metabolism; Female; Male; Mast Cells/immunology/metabolism/pathology; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, Knockout; Mice, Transgenic; Neuropeptides/deficiency/genetics/*immunology; Protein Isoforms/deficiency/genetics/immunology; Receptors, Neurotensin/deficiency/genetics/immunology; Receptors, Neurotransmitter/deficiency/genetics/*immunology; Spleen/immunology/metabolism/pathology |
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Author: Smith, B. R.; Kempen, P.; Bouley, D.; Xu, A.; Liu, Z.; Melosh, N.; Dai, H.; Sinclair, R.; Gambhir, S. S. |
Title: Shape matters: intravital microscopy reveals surprising geometrical dependence for nanoparticles in tumor models of extravasation |
Year: 2012 |
Publication: Nano Lett |
Volume: 12 |
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Keywords: AngioSense, Animals; *Disease Models, Animal; Ear Neoplasms/*blood supply/pathology; Humans; Mice; Microscopy, Fluorescence; Nanoparticles/*chemistry; *Nanotechnology; Nanotubes, Carbon/chemistry; Neoplasms, Experimental/*blood supply/pathology; Particle Size; Quantum Dots; Surface Properties |
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Author: Clare Piper, Pat G. Casey, Colin Hill, Paul D. Cotter, and R. Paul Ross |
Title: The Lantibiotic Lacticin 3147 Prevents Systemic Spread of Staphylococcus aureus in a Murine Infection Model |
Year: 2012 |
Publication: International Journal of Microbiology |
Volume: 2012 |
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Keywords: IVIS, Xen29, Xen 29, Staphylococcus aureus Xen29 |
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Author: Hsieh, C. H.; Chang, H. T.; Shen, W. C.; Shyu, W. C.; Liu, R. S. |
Title: Imaging the impact of Nox4 in cycling hypoxia-mediated U87 glioblastoma invasion and infiltration |
Year: 2012 |
Publication: Mol Imaging Biol |
Volume: 14 |
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Keywords: MMPSense, IVIS, Animals; Cell Hypoxia; Cell Line, Tumor; Cell Movement; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases/metabolism; Gene Knockdown Techniques; Glioblastoma/*enzymology/*pathology; Humans; JNK Mitogen-Activated Protein Kinases/metabolism; Matrix Metalloproteinase 9/metabolism; Mice; Mice, SCID; Molecular Imaging/*methods; NADPH Oxidase/*metabolism; NF-kappa B/metabolism; Neoplasm Invasiveness; Reactive Oxygen Species/metabolism; Tumor Microenvironment; Xenograft Model Antitumor Assays |
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Author: Chen, Y.; Jacamo, R.; Shi, Y. X.; Wang, R. Y.; Battula, V. L.; Konoplev, S.; Strunk, D.; Hofmann, N. A.; Reinisch, A.; Konopleva, M.; Andreeff, M. |
Title: Human extramedullary bone marrow in mice: a novel in vivo model of genetically controlled hematopoietic microenvironment |
Year: 2012 |
Publication: Blood |
Volume: 119 |
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Keywords: OsteoSense, IVIS, Animals; Bone Marrow Cells/*cytology/metabolism/physiology; Bone Marrow Transplantation/*methods/physiology; Cells, Cultured; Cellular Microenvironment/genetics/*physiology; Hematopoiesis, Extramedullary/genetics/*physiology; Humans; Hypoxia-Inducible Factor 1, alpha Subunit/genetics/metabolism; Interleukin Receptor Common gamma Subunit/genetics; Mice; Mice, Inbred NOD; Mice, SCID; Mice, Transgenic; Models, Animal; Osteogenesis/genetics/physiology; Species Specificity; *Transplantation, Heterotopic |
