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Author: Cabral, Horacio; Nishiyama, Nobuhiro; Kataoka, Kazunori | Title: Optimization of (1,2-diamino-cyclohexane)platinum(II)-loaded polymeric micelles directed to improved tumor targeting and enhanced antitumor activity | Year: 2007 | Publication: Journal of controlled release: official journal of the Controlled Release Society | Volume: 121 | Products: | Keywords: Animals; Antineoplastic Agents; Bioware; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Female; Hela Cells; HeLa-luc; Humans; Mice; Mice, SCID; Micelles; Neoplasms; Organoplatinum Compounds; Platinum; Polymers; Xenograft Model Antitumor Assays |
Author: Cheung, R.; Shen, F.; Phillips, J. H.; McGeachy, M. J.; Cua, D. J.; Heyworth, P. G.; Pierce, R. H. | Title: Activation of MDL-1 (CLEC5A) on immature myeloid cells triggers lethal shock in mice | Year: 2011 | Publication: J Clin Invest | Volume: 121 | Products: | Keywords: IVIS, RediJect Inflammation Probe, chemiluminescence, XenoLight, Adaptor Proteins, Signal Transducing/metabolism; Animals; Cell Differentiation; Concanavalin A/toxicity; Dengue Hemorrhagic Fever/etiology; Disease Models, Animal; Disease Progression; Female; Humans; Immunity, Innate; Intracellular Signaling Peptides and Proteins/metabolism; Lectins, C-Type/deficiency/genetics/*immunology; Liver/metabolism/pathology; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Immunological; Myeloid Cells/*immunology/pathology; Nitric Oxide/biosynthesis; Nitric Oxide Synthase Type II/metabolism; Nitric Oxide Synthase Type III/metabolism; Phosphatidylinositol 3-Kinases/metabolism; Protein-Tyrosine Kinases/metabolism; Proto-Oncogene Proteins c-akt/metabolism; Receptors, Cell Surface/deficiency/genetics/*immunology; Receptors, Immunologic/metabolism; Shock/*etiology/*immunology/metabolism/pathology; Signal Transduction; Systemic Inflammatory Response; Syndrome/etiology/immunology/metabolism/pathology; Tumor Necrosis Factor-alpha/biosynthesis |
Author: Thomas Christen, Matthias Nahrendorf, Moritz Wildgruber, Filip K. Swirski, Elena Aikawa, Peter Waterman, Koichi Shimizu, Ralph Weissleder and Peter Libby | Title: Molecular Imaging of Innate Immune Cell Function in Transplant Rejection | Year: 2009 | Publication: Circulation | Volume: 119 | Products: | Keywords: In vivo imaging; inflammation; leukocytes; rejection; transplantation; fluorescence molecular tomography; FMT; Prosense |
Author: Chiara Buono, Joshua J. Anzinger, Marcelo Amar and Howard S. Kruth | Title: Fluorescent pegylated nanoparticles demonstrate fluid-phase pinocytosis by macrophages in mouse atherosclerotic lesions | Year: 2009 | Publication: The Journal of Clinical Investigation | Volume: 119 | Products: | Keywords: In vivo imaging; AngioSPARK |
Author: | Title: | Year: 2009 | Publication: Circulation | Volume: 119 | Products: | Keywords: In vivo imaging; MMPSense |
Author: Wallis de Vries, B. M.; Hillebrands, J. L.; van Dam, G. M.; Tio, R. A.; de Jong, J. S.; Slart, R. H.; Zeebregts, C. J. | Title: Images in cardiovascular medicine. Multispectral near-infrared fluorescence molecular imaging of matrix metalloproteinases in a human carotid plaque using a matrix-degrading metalloproteinase-sensitive activatable fluorescent probe | Year: 2009 | Publication: Circulation | Volume: 119 | Products: | Keywords: MMPSense, IVIS, Aged; Carotid Artery Diseases/diagnosis/enzymology/*pathology; Diagnostic Imaging/methods; Female; Humans; Matrix Metalloproteinase 9/analysis; Matrix Metalloproteinases/*analysis; Spectroscopy, Near-Infrared/*methods; Tissue Distribution |
Author: Chen, Y.; Jacamo, R.; Shi, Y. X.; Wang, R. Y.; Battula, V. L.; Konoplev, S.; Strunk, D.; Hofmann, N. A.; Reinisch, A.; Konopleva, M.; Andreeff, M. | Title: Human extramedullary bone marrow in mice: a novel in vivo model of genetically controlled hematopoietic microenvironment | Year: 2012 | Publication: Blood | Volume: 119 | Products: | Keywords: OsteoSense, IVIS, Animals; Bone Marrow Cells/*cytology/metabolism/physiology; Bone Marrow Transplantation/*methods/physiology; Cells, Cultured; Cellular Microenvironment/genetics/*physiology; Hematopoiesis, Extramedullary/genetics/*physiology; Humans; Hypoxia-Inducible Factor 1, alpha Subunit/genetics/metabolism; Interleukin Receptor Common gamma Subunit/genetics; Mice; Mice, Inbred NOD; Mice, SCID; Mice, Transgenic; Models, Animal; Osteogenesis/genetics/physiology; Species Specificity; *Transplantation, Heterotopic |
Author: Virna Cortez-Retamozo, Filip K. Swirski, Peter Waterman, Hushan Yuan, Jose Luiz Figueiredo, Andita P. Newton, Rabi Upadhyay, Claudio Vinegoni, Rainer Kohler, Joseph Blois, Adam Smith, Matthias Nahrendorf, Lee Josephson, Ralph Weissleder and Mikael J. Pittet | Title: Real-time assessment of inflammation and treatment response in a mouse model of allergic airway inflammation | Year: 2008 | Publication: Journal of Clinical Investigation | Volume: 118 | Products: | Keywords: FMT; in vivo imaging; ProSense; MMPSense |
Author: Jose-Luiz Figueiredo, Herlen Alencar, Ralph Weissleder and Umar Mahmood | Title: Near infrared thoracoscopy of tumoral protease activity for improved detection of peripheral lung cancer | Year: 2006 | Publication: International Journal of Cancer | Volume: 118 | Products: | Keywords: ProSense; adenocarcinoma; thoracoscopy; VATS; optical probes; near infrared fluorescence imaging; in vivo imaging |
Author: Farouc A. Jaffer, Claudio Vinegoni, Michael C. John, Elena Aikawa, Herman K. Gold, Aloke V. Finn, Vasilis Ntziachristos, Peter Libby and Ralph Weissleder | Title: Real-Time Catheter Molecular Sensing of Inflammation in Proteolytically Active Atherosclerosis | Year: 2008 | Publication: Circulation | Volume: 118 | Products: | Keywords: atherosclerosis; catheters; fluorescence; imaging; inflammation; cathepsins; in vivo imaging; ProSense |