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Author: David G Kirsch; Daniela M Dinulescu; John B Miller; Jan Grimm; Philip M Santiago1; Nathan P Young; G Petur Nielsen; Bradley J Quade; Christopher J Chaber; Christian P Schultz; Osamu Takeuchi; Roderick T Bronson; Denise Crowley; Stanley J Korsmeyer; Sam S Yoon; Francis J Hornicek; Ralph Weissleder; Tyler Jacks |
Title: A spatially and temporally restricted mouse model of soft tissue sarcoma |
Year: 2007 |
Publication: Nature Medicine |
Volume: 13 |
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Keywords: sarcoma; imaging; apoptosis; metatasis; FMT |
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Author: Georgel, Philippe; Crozat, Karine; Lauth, Xavier; Makrantonaki, Evgenia; Seltmann, Holger; Sovath, Sosathya; Hoebe, Kasper; Du, Xin; Rutschmann, Sophie; Jiang, Zhengfan; Bigby, Timothy; Nizet, Victor; Zouboulis, Christos C; Beutler, Bruce |
Title: A toll-like receptor 2-responsive lipid effector pathway protects mammals against skin infections with gram-positive bacteria |
Year: 2005 |
Publication: Infection and immunity |
Volume: 73 |
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Keywords: Animals; Anti-Bacterial Agents; Bioware; Chromosome Mapping; Eye Diseases; Fatty Acids, Monounsaturated; Likelihood Functions; Lod Score; Mice; Mice, Inbred C57BL; Oleic Acid; Receptors, Immunologic; Sequence Analysis, DNA; Skin; Staphylococcal Skin Infections; Stearoyl-CoA Desaturase; Streptococcus pyogenes; Time Factors; Toll-Like Receptor 2; Xen8.1, Xen20, Xen14 |
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Author: Bethunaickan, R.; Berthier, C.C.; Ramanujam, M.; Sahu, R.; Zhang, W.; Sun, Y.; Bottinger, E.P.; Ivashkiv, L.; Kretzler, M.; Davidson, A. |
Title: A Unique Hybrid Renal Mononuclear Phagocyte Activation Phenotype in Murine Systemic Lupus Erythematosus Nephritis |
Year: 2011 |
Publication: Journal of Immunology (Baltimore, Md.: 1950) |
Volume: |
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Keywords: In vivo; kidney; mice; MMPSense 680; ProSense 680 |
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Author: Las Heras, F.; DaCosta, R. S.; Pritzker, K. P.; Haroon, N.; Netchev, G.; Tsui, H. W.; Chiu, B.; Erwin, W. M.; Tsui, F. W.; Inman, R. D. |
Title: Aberrant axial mineralization precedes spinal ankylosis: a molecular imaging study in ank/ank mice |
Year: 2011 |
Publication: Arthritis Res Ther |
Volume: 13 |
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Keywords: OsteoSense, Animals; Axis/chemistry/*metabolism/*pathology; *Calcification, Physiologic/genetics; Inflammation/genetics/metabolism/prevention & control; Mice; Mice, Transgenic; Molecular Imaging/*methods; Spondylitis, Ankylosing/diagnosis/*genetics/*metabolism; Time Factors |
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Author: Stangenberg L, Ellson C, Cortez-Retamozo V, Ortiz-Lopez A, Yuan H, Blois J, Smith RA, Yaffe MB, Weissleder R, Benoist C, Mathis D, Josephson L and Mahmood U |
Title: Abrogation of antibody-induced arthritis in mice by a self-activating viridin prodrug and association with impaired neutrophil and endothelial cell function |
Year: 2009 |
Publication: Arthritis and Rheumatism |
Volume: 60 |
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Keywords: ProSense; AngioSense; arthritis; in vivo imaging |
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Author: Palma, Joann P; Wang, Yi-Chun; Rodriguez, Luis E; Montgomery, Debra; Ellis, Paul A; Bukofzer, Gail; Niquette, Amanda; Liu, Xuesong; Shi, Yan; Lasko, Loren; Zhu, Gui-Dong; Penning, Thomas D; Giranda, Vincent L; Rosenberg, Saul H; Frost, David J; Donawho, Cherrie K |
Title: ABT-888 confers broad in vivo activity in combination with temozolomide in diverse tumors |
Year: 2009 |
Publication: Clinical cancer research: an official journal of the American Association for Cancer Research |
Volume: 15 |
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Keywords: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Bioware; Dacarbazine; DNA Damage; DNA Modification Methylases; DNA Repair; DNA Repair Enzymes; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; MDA-MB-231-D3H2LN cells; Mice; Mice, SCID; Neoplasm Metastasis; Neoplasm Transplantation; Tumor Suppressor Proteins |
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Author: Subbarayan, P. R.; Sarkar, M.; Nagaraja Rao, S.; Philip, S.; Kumar, P.; Altman, N.; Reis, I.; Ahmed, M.; Ardalan, B.; Lokeshwar, B. L. |
Title: Achyranthes aspera (Apamarg) leaf extract inhibits human pancreatic tumor growth in athymic mice by apoptosis |
Year: 2012 |
Publication: J Ethnopharmacol |
Volume: 142 |
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Keywords: BxPC-3, BxPC-3-luc2, IVIS, Achyranthes; Animals; Antineoplastic Agents, Phytogenic/pharmacology/*therapeutic use; Apoptosis/*drug effects; Caspase 3/genetics/metabolism; Gene Expression/drug effects; Humans; Injections, Intraperitoneal; Medicine, Ayurvedic; Mice; Mice, Nude; Pancreatic Neoplasms/*drug therapy/genetics/metabolism; Phosphorylation; *Phytotherapy; Plant Extracts/pharmacology/*therapeutic use; Plant Leaves; Proto-Oncogene Proteins c-akt/metabolism; RNA, Messenger/metabolism; Xenograft Model Antitumor Assays |
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Author: Smith, Eric L; Schuchman, Edward H |
Title: Acid sphingomyelinase overexpression enhances the antineoplastic effects of irradiation in vitro and in vivo |
Year: 2008 |
Publication: Molecular therapy: the journal of the American Society of Gene Therapy |
Volume: 16 |
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Keywords: Animals; Antineoplastic Agents; Autophagy; B16-F10-luc-G5 cells; Bioware; Cell Survival; Cells, Cultured; Ceramides; Cesium Radioisotopes; CHO Cells; Combined Modality Therapy; Cricetinae; Cricetulus; Endothelium, Vascular; Female; Gamma Rays; Gene Expression Regulation, Enzymologic; Gene Therapy; Humans; Melanoma, Experimental; Mice; Sphingomyelin Phosphodiesterase |
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Author: Cheung, R.; Shen, F.; Phillips, J. H.; McGeachy, M. J.; Cua, D. J.; Heyworth, P. G.; Pierce, R. H. |
Title: Activation of MDL-1 (CLEC5A) on immature myeloid cells triggers lethal shock in mice |
Year: 2011 |
Publication: J Clin Invest |
Volume: 121 |
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Keywords: IVIS, RediJect Inflammation Probe, chemiluminescence, XenoLight, Adaptor Proteins, Signal Transducing/metabolism; Animals; Cell Differentiation; Concanavalin A/toxicity; Dengue Hemorrhagic Fever/etiology; Disease Models, Animal; Disease Progression; Female; Humans; Immunity, Innate; Intracellular Signaling Peptides and Proteins/metabolism; Lectins, C-Type/deficiency/genetics/*immunology; Liver/metabolism/pathology; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Immunological; Myeloid Cells/*immunology/pathology; Nitric Oxide/biosynthesis; Nitric Oxide Synthase Type II/metabolism; Nitric Oxide Synthase Type III/metabolism; Phosphatidylinositol 3-Kinases/metabolism; Protein-Tyrosine Kinases/metabolism; Proto-Oncogene Proteins c-akt/metabolism; Receptors, Cell Surface/deficiency/genetics/*immunology; Receptors, Immunologic/metabolism; Shock/*etiology/*immunology/metabolism/pathology; Signal Transduction; Systemic Inflammatory Response; Syndrome/etiology/immunology/metabolism/pathology; Tumor Necrosis Factor-alpha/biosynthesis |
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Author: Rosenzweig HL, Jann MM, Glant TT, Martin TM, Planck SR, van Eden W, van Kooten PJ, Flavell RA, Kobayashi KS, Rosenbaum JT and Davey MP |
Title: Activation of nucleotide oligomerization domain 2 exacerbates a murine model of proteoglycan-induced arthritis |
Year: 2009 |
Publication: Journal of Leukocyte Biology |
Volume: 85 |
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Keywords: ProSense; in vivo imaging; NOD2; mice; inflammatory arthritis; TCR transgenic; knockout |
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