|
|
Author: Takeshita, Fumitaka; Patrawala, Lubna; Osaki, Mitsuhiko; Takahashi, Ryou-u; Yamamoto, Yusuke; Kosaka, Nobuyoshi; Kawamata, Masaki; Kelnar, Kevin; Bader, Andreas G; Brown, David; Ochiya, Takahiro |
Title: Systemic delivery of synthetic microRNA-16 inhibits the growth of metastatic prostate tumors via downregulation of multiple cell-cycle genes |
Year: 2010 |
Publication: Molecular therapy: the journal of the American Society of Gene Therapy |
Volume: 18 |
Products: |
Keywords: Aged; Animals; Bioware; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Humans; Male; Mice; MicroRNAs; Middle Aged; PC-3M-luc; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction |
|
|
Author: |
Title: Synthetic cationic peptide IDR-1002 provides protection against bacterial infections through chemokine induction and enhanced leukocyte recruitment |
Year: 2010 |
Publication: Journal of immunology (Baltimore, Md.: 1950) |
Volume: 184 |
Products: |
Keywords: Amino Acid Sequence; Animals; Antimicrobial Cationic Peptides; Bacterial Infections; Bioware; Cell Line; Cells, Cultured; Chemokine CCL2; Chemokine CCL7; Chemokine CXCL1; Chemokines; Female; Humans; Interleukin-8; Leukocytes; Leukocytes, Mononuclear; Macrophages; Mice; Mice, Inbred C57BL; Molecular Sequence Data; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Staphylococcal Infections; Staphylococcus aureus; Xen29, Xen14 |
|
|
Author: Nijnik, A.; Madera, L.; Ma, S.; Waldbrook, M.; Elliott, M. R.; Easton, D. M.; Mayer, M. L.; Mullaly, S. C.; Kindrachuk, J.; Jenssen, H.; Hancock, R. E. |
Title: Synthetic cationic peptide IDR-1002 provides protection against bacterial infections through chemokine induction and enhanced leukocyte recruitment |
Year: 2010 |
Publication: J Immunol |
Volume: 184 |
Products: |
Keywords: Xen14, Xen 14, E. coli Xen14, IVIS, Amino Acid Sequence; Animals; Antimicrobial Cationic Peptides/chemical synthesis/*pharmacology; Bacterial Infections/*metabolism/microbiology/prevention & control; Cell Line; Cells, Cultured; Chemokine CCL2/metabolism; Chemokine CCL7/metabolism; Chemokine CXCL1/metabolism; Chemokines/*metabolism; Female; Humans; Interleukin-8/metabolism; Leukocytes/cytology/*metabolism; Leukocytes, Mononuclear/cytology/drug effects/metabolism; Macrophages/cytology/drug effects/metabolism; Mice; Mice, Inbred C57BL; Molecular Sequence Data; NF-kappa B/metabolism; Phosphatidylinositol 3-Kinases/metabolism; Phosphorylation/drug effects; Staphylococcal Infections/microbiology/prevention & control; Staphylococcus aureus/drug effects; p38 Mitogen-Activated Protein Kinases/metabolism |
|
|
Author: Qamri, Zahida; Preet, Anju; Nasser, Mohd W; Bass, Caroline E; Leone, Gustavo; Barsky, Sanford H; Ganju, Ramesh K |
Title: Synthetic cannabinoid receptor agonists inhibit tumor growth and metastasis of breast cancer |
Year: 2009 |
Publication: Molecular cancer therapeutics |
Volume: 8 |
Products: |
Keywords: Animals; Apoptosis; Benzoxazines; Bioware; Breast Neoplasms; Cannabinoids; Cell Cycle; Cell Growth Processes; Cell Line, Tumor; Cell Movement; Cyclooxygenase 2; Dinoprostone; Female; Humans; Immunohistochemistry; Lung Neoplasms; Male; Mammary Neoplasms, Experimental; MDA-MB-231-D3H2LN cells; Mice; Mice, Inbred C3H; Mice, SCID; Mice, Transgenic; Microscopy, Confocal; Morpholines; Naphthalenes; Neoplasm Metastasis; Neovascularization, Pathologic; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; RNA, Small Interfering; Signal Transduction; Transfection; Xenograft Model Antitumor Assays |
|
|
Author: Tafreshi, N. K.; Huang, X.; Moberg, V. E.; Barkey, N. M.; Sondak, V. K.; Tian, H.; Morse, D. L.; Vagner, J. |
Title: Synthesis and Characterization of a Melanoma-Targeted Fluorescence Imaging Probe by Conjugation of a Melanocortin 1 Receptor (MC1R) Specific Ligand |
Year: 2012 |
Publication: Bioconjug Chem |
Volume: 23 |
Products: |
Keywords: IVIS, B16-F10-luc-G5, B16F10-luc-G5, B16-F10-luc, B16F10-luc |
|
|
Author: Yang, Li; Johansson, Jan; Ridsdale, Ross; Willander, Hanna; Fitzen, Michael; Akinbi, Henry T; Weaver, Timothy E |
Title: Surfactant protein B propeptide contains a saposin-like protein domain with antimicrobial activity at low pH |
Year: 2010 |
Publication: Journal of immunology (Baltimore, Md.: 1950) |
Volume: 184 |
Products: |
Keywords: Animals; Anti-Bacterial Agents; Bronchoalveolar Lavage Fluid; Hydrogen-Ion Concentration; Immunity, Innate; Klebsiella pneumoniae; Macrophages, Alveolar; Mice; Mice, Transgenic; Protein Precursors; Protein Structure, Tertiary; Proteolipids; Saposins; Staphylococcus aureus; Tissue Distribution; Xen5 |
|
|
Author: Evans, L.; Williams, A. S.; Hayes, A. J.; Jones, S. A.; Nowell, M. |
Title: Suppression of leukocyte infiltration and cartilage degradation by selective inhibition of pre-B cell colony-enhancing factor/visfatin/nicotinamide phosphoribosyltransferase: Apo866-mediated therapy in human fibroblasts and murine collagen-induced arthritis |
Year: 2011 |
Publication: Arthritis Rheum |
Volume: 63 |
Products: |
Keywords: MMPSense, IVIS, Acrylamides/pharmacology/*therapeutic use; Animals; Arthritis, Experimental/*drug therapy/metabolism/pathology; Cartilage/*metabolism/pathology; Fibroblasts/metabolism/pathology; Humans; Inflammation/metabolism/pathology; Leukocytes/*drug effects/metabolism/pathology; Mice; Nicotinamide Phosphoribosyltransferase/*antagonists & inhibitors; Piperidines/pharmacology/*therapeutic use |
|
|
Author: Zhuang, H.; Jiang, W.; Zhang, X.; Qiu, F.; Gan, Z.; Cheng, W.; Zhang, J.; Guan, S.; Tang, B.; Huang, Q.; Wu, X.; Huang, X.; Hu, Q.; Lu, M.; Hua, Z. C. |
Title: Suppression of HSP70 expression sensitizes NSCLC cell lines to TRAIL-induced apoptosis by upregulating DR4 and DR5 and downregulating c-FLIP-L expressions |
Year: 2012 |
Publication: J Mol Med (Berl) |
Volume: |
Products: |
Keywords: A549-luc-C8, A549-luc, IVIS, Bioware |
|
|
Author: Matsumoto, K.; Azami, T.; Otsu, A.; Takase, H.; Ishitobi, H.; Tanaka, J.; Miwa, Y.; Takahashi, S.; Ema, M. |
Title: Study of normal and pathological blood vessel morphogenesis in Flt1-tdsRed BAC Tg mice |
Year: 2012 |
Publication: Genesis |
Volume: 50 |
Products: |
Keywords: AngioSense, Animals; Blood Vessels/embryology/*physiology; Chromosomes, Artificial, Bacterial; Embryo, Mammalian; Endothelial Cells/cytology/metabolism; Endothelium, Vascular/cytology/embryology/metabolism; Female; Founder Effect; Gene Expression Regulation, Developmental; Genes, Reporter; Mice; *Mice, Transgenic; Microscopy, Fluorescence; Morphogenesis/physiology; *Neovascularization, Pathologic; *Neovascularization, Physiologic; Retina/embryology/*physiology; Vascular Endothelial Growth Factor A/genetics/metabolism; Vascular Endothelial Growth Factor Receptor-1/genetics/*metabolism; Vascular Endothelial Growth Factor Receptor-2/genetics/metabolism |
|
|
Author: Li, Min; Rigby, Kevin; Lai, Yuping; Nair, Vinod; Peschel, Andreas; Schittek, Birgit; Otto, Michael |
Title: Staphylococcus aureus mutant screen reveals interaction of the human antimicrobial peptide dermcidin with membrane phospholipids |
Year: 2009 |
Publication: Antimicrobial agents and chemotherapy |
Volume: 53 |
Products: |
Keywords: Anti-Bacterial Agents; Bioware; Blotting, Southern; Chromatography, Thin Layer; Computational Biology; Cytochromes c; Genetic Complementation Test; Humans; Microscopy, Electron, Scanning; Microscopy, Immunoelectron; Mutagenesis; Peptides; Phospholipids; Polymerase Chain Reaction; Staphylococcus aureus; Xen36 |
