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Author: Mulivor, A.W.; Barbosa, D.; Kumar, R.; Pearsall, A.E.; Underwood, K.W.; Ucran, J.A.; Seehra, J.; Pearsall, R. |
Title: RAP-011, a soluble activin receptor type IIA murine IgG-Fc fusion protein, is a novel bone anabolic agent that prevents bone loss and skeletal metastases in a mouse model of metastatic breast cancer |
Year: 2009 |
Publication: Bone |
Volume: 44 |
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Keywords: Bioware; MDA-MB-231-D3H2LN cells |
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Author: Casarez, Eli V; Dunlap-Brown, Marya E; Conaway, Mark R; Amorino, George P |
Title: Radiosensitization and modulation of p44/42 mitogen-activated protein kinase by 2-Methoxyestradiol in prostate cancer models |
Year: 2007 |
Publication: Cancer research |
Volume: 67 |
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Keywords: Animals; Bioware; Carcinoma; Estradiol; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; PC-3M-luc; Phosphorylation; Prostatic Neoplasms; Radiation-Sensitizing Agents; Subcutaneous Tissue; Transplantation, Heterotopic; Tumor Cells, Cultured; Xenograft Model Antitumor Assays |
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Author: Holland, Sacha J; Pan, Alison; Franci, Christian; Hu, Yuanming; Chang, Betty; Li, Weiqun; Duan, Matt; Torneros, Allan; Yu, Jiaxin; Heckrodt, Thilo J; Zhang, Jing; Ding, Pingyu; Apatira, Ayodele; Chua, Joanne; Brandt, Ralf; Pine, Polly; Goff, Dane; Singh, Rajinder; Payan, Donald G; Hitoshi, Yasumichi |
Title: R428, a selective small molecule inhibitor of Axl kinase, blocks tumor spread and prolongs survival in models of metastatic breast cancer |
Year: 2010 |
Publication: Cancer research |
Volume: 70 |
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Keywords: Animals; Antineoplastic Agents; Benzocycloheptenes; Bioware; Breast Neoplasms; Carcinoma; Female; Hela Cells; Humans; K562 Cells; MDA-MB-231-D3H2LN cells; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Oncogene Proteins; Protein kinase inhibitors; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Survival Analysis; Triazoles; Tumor Cells, Cultured; Xenograft Model Antitumor Assays |
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Title: Quantitative mouse model of implant-associated osteomyelitis and the kinetics of microbial growth, osteolysis, and humoral immunity |
Year: 2008 |
Publication: Journal of orthopaedic research: official publication of the Orthopaedic Research Society |
Volume: 26 |
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Keywords: Animals; Antibody Formation; Bacterial Proteins; Bioware; Disease Models, Animal; DNA, Bacterial; Endonucleases; Female; Mice; Mice, Inbred C57BL; Micrococcal Nuclease; Osteolysis; Osteomyelitis; Prosthesis-Related Infections; Reverse Transcriptase Polymerase Chain Reaction; Staphylococcal Infections; Staphylococcus aureus; Tibia; Xen29 |
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Author: Lin, S. A.; Patel, M.; Suresch, D.; Connolly, B.; Bao, B.; Groves, K.; Rajopadhye, M.; Peterson, J. D.; Klimas, M.; Sur, C.; Bednar, B. |
Title: Quantitative Longitudinal Imaging of Vascular Inflammation and Treatment by Ezetimibe in apoE Mice by FMT Using New Optical Imaging Biomarkers of Cathepsin Activity and alpha(v)beta(3) Integrin |
Year: 2012 |
Publication: Int J Mol Imaging |
Volume: 2012 |
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Keywords: FMT, Prosense, CatB, Cathepsin B, fluorescence imaing, tomography, microCT |
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Author: Proulx, S. T.; Luciani, P.; Derzsi, S.; Rinderknecht, M.; Mumprecht, V.; Leroux, J. C.; Detmar, M. |
Title: Quantitative imaging of lymphatic function with liposomal indocyanine green |
Year: 2010 |
Publication: Cancer Res |
Volume: 70 |
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Keywords: Animals, B16-F10-luc2, B16F10-luc2; Coloring Agents/administration & dosage/*diagnostic use; Indocyanine Green/administration & dosage/*diagnostic use; Injections, Intradermal; Liposomes/administration & dosage; Lymphatic Metastasis; Lymphatic Vessels/metabolism/*pathology; Melanoma, Experimental/blood supply/metabolism/*pathology; Mice; Mice, Inbred C57BL; Vascular Endothelial Growth Factor C/biosynthesis |
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Author: Nguyen, Leslie; Zhong, Wei-Zhu; Painter, Cory L; Zhang, Cathy; Rahavendran, Sadayappan V; Shen, Zhongzhou |
Title: Quantitative analysis of PD 0332991 in xenograft mouse tumor tissue by a 96-well supported liquid extraction format and liquid chromatography/mass spectrometry |
Year: 2010 |
Publication: Journal of pharmaceutical and biomedical analysis |
Volume: 53 |
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Keywords: Animals; Bioware; Chromatography, Liquid; Cyclin-Dependent Kinase 4; Drug Stability; Female; Humans; MDA-MB-231-D3H1 cells; Mice; Mice, SCID; Neoplasm Transplantation; Neoplasms, Experimental; Piperazines; Protein kinase inhibitors; Pyridines; Sensitivity and Specificity; Tandem Mass Spectrometry; Transplantation, Heterologous |
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Author: Rambow-Larsen, Amy A; Rajashekara, Gireesh; Petersen, Erik; Splitter, Gary |
Title: Putative quorum-sensing regulator BlxR of Brucella melitensis regulates virulence factors including the type IV secretion system and flagella |
Year: 2008 |
Publication: Journal of bacteriology |
Volume: 190 |
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Keywords: Amino Acid Sequence; Animals; Bioware; Brucella melitensis; Brucellosis; Disease Models, Animal; Flagella; Gene Deletion; Gene Expression Regulation, Bacterial; Interferon Regulatory Factor-1; Macrophages; Mice; Mice, Mutant Strains; Molecular Sequence Data; Oligonucleotide Array Sequence Analysis; pXen-13; Quorum Sensing; Repressor Proteins; Trans-Activators; Virulence Factors |
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Author: Huang, Yujie; Song, Nan; Ding, Yanping; Yuan, Shaopeng; Li, Xuhui; Cai, Hongchen; Shi, Hubing; Luo, Yongzhang |
Title: Pulmonary vascular destabilization in the premetastatic phase facilitates lung metastasis |
Year: 2009 |
Publication: Cancer research |
Volume: 69 |
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Keywords: Angiopoietin-2; Animals; Bioware; Breast Neoplasms; Capillary Permeability; Female; Gene Expression; Humans; Lung; Lung Neoplasms; Matrix Metalloproteinase 10; Matrix Metalloproteinase 3; MDA-MB-231-D3H1 cells; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Nude; RNA Interference; Up-Regulation |
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Author: Heit, Bryan; Robbins, Stephen M; Downey, Charlene M; Guan, Zhiwen; Colarusso, Pina; Miller, B Joan; Jirik, Frank R; Kubes, Paul |
Title: PTEN functions to 'prioritize' chemotactic cues and prevent 'distraction' in migrating neutrophils |
Year: 2008 |
Publication: Nature immunology |
Volume: 9 |
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Keywords: Animals; Arthritis, Experimental; Bioware; Chemotaxis, Leukocyte; Humans; Inflammation; Mice; Mice, Transgenic; Neutrophils; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Phosphates; Protein Transport; PTEN Phosphohydrolase; Xen29 |
