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Author: Cheng, H. H.; Kuo, C. C.; Yan, J. L.; Chen, H. L.; Lin, W. C.; Wang, K. H.; Tsai, K. K.; Guven, H.; Flaberg, E.; Szekely, L.; Klein, G.; Wu, K. K. |
Title: Control of cyclooxygenase-2 expression and tumorigenesis by endogenous 5-methoxytryptophan |
Year: 2012 |
Publication: Proc Natl Acad Sci U S A |
Volume: 109 |
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Keywords: A549-luc-C8, A549-luc, IVIS, Bioware, Acetylserotonin O-Methyltransferase/metabolism; Animals; Biocatalysis/drug effects; Cell Line, Tumor; Cell Movement/drug effects; Cell Proliferation/drug effects; Cell Transformation, Neoplastic/drug effects/*pathology; Cyclooxygenase 2/*metabolism; Cyclooxygenase 2 Inhibitors/pharmacology; Fibroblasts/drug effects/metabolism; Humans; Metabolic Networks and Pathways/drug effects; Metabolomics; Mice; Neoplasm Metastasis; Solubility/drug effects; Subcellular Fractions/drug effects/metabolism; Tryptophan/*analogs & derivatives/biosynthesis/metabolism/pharmacology; Tryptophan Hydroxylase/metabolism; Xenograft Model Antitumor Assays |
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Author: Goldberg, M. S.; Xing, D.; Ren, Y.; Orsulic, S.; Bhatia, S. N.; Sharp, P. A. |
Title: Nanoparticle-mediated delivery of siRNA targeting Parp1 extends survival of mice bearing tumors derived from Brca1-deficient ovarian cancer cells |
Year: 2011 |
Publication: Proc Natl Acad Sci U S A |
Volume: 108 |
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Keywords: VivoTag, IVIS, Vivotag, Animals; BRCA1 Protein/*genetics; Drug Carriers; Drug Delivery Systems; Female; Humans; Mice; Nanoparticles/*chemistry; Nanotechnology/methods; Neoplasm Transplantation; Ovarian Neoplasms/*genetics/*therapy; Poly(ADP-ribose) Polymerases/*genetics; RNA Interference; RNA, Small Interfering/*metabolism; Treatment Outcome |
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Author: Goldberg, M.S.; Xing, D.; Ren, Y.; Orsulic, S.; Bhatia, S.N.; Sharp, P.A. |
Title: Nanoparticle-mediated delivery of siRNA targeting Parp1 extends survival of mice bearing tumors derived from Brca1-deficient ovarian cancer cells |
Year: 2011 |
Publication: Proceedings of the National Academy of Sciences of the United States of America |
Volume: 108 |
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Keywords: brca1; Cancer; In vivo imaging (VisEn); IVIS Spectrum imaging system; mice; siRNA; vivotag-750 |
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Author: Quintela-Fandino, Miguel; Arpaia, Enrico; Brenner, Dirk; Goh, Theo; Yeung, Faith Au; Blaser, Heiko; Alexandrova, Roumiana; Lind, Evan F; Tusche, Mike W; Wakeham, Andrew; Ohashi, Pamela S; Mak, Tak W |
Title: HUNK suppresses metastasis of basal type breast cancers by disrupting the interaction between PP2A and cofilin-1 |
Year: 2010 |
Publication: Proceedings of the National Academy of Sciences of the United States of America |
Volume: 107 |
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Keywords: Actins; Animals; B16-F10-luc-G5; Bioware; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cofilin 1; Cytoskeleton; Female; Humans; Immunoblotting; Immunoprecipitation; Male; Mammary Neoplasms, Experimental; MDA-MB-231-D3H2LN cells; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Invasiveness; Neoplasm Metastasis; Phosphorylation; Protein Binding; Protein Kinases; Protein Phosphatase 2; Protein-Serine-Threonine Kinases; RNA Interference; Transplantation, Heterologous |
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Author: Takeshita, Fumitaka; Minakuchi, Yoshiko; Nagahara, Shunji; Honma, Kimi; Sasaki, Hideo; Hirai, Kotaro; Teratani, Takumi; Namatame, Nachi; Yamamoto, Yusuke; Hanai, Koji; Kato, Takashi; Sano, Akihiko; Ochiya, Takahiro |
Title: Efficient delivery of small interfering RNA to bone-metastatic tumors by using atelocollagen in vivo |
Year: 2005 |
Publication: Proceedings of the National Academy of Sciences of the United States of America |
Volume: 102 |
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Keywords: Animals; Bioware; Bone Neoplasms; Cell Line, Tumor; Collagen; DNA-Binding Proteins; Drug Carriers; Gene Expression Regulation, Neoplastic; Gene Therapy; Humans; Luciferases; Male; Mice; PC-3M-luc; Phosphatidylinositol 3-Kinases; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Transcription Factors |
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Author: Woelfle, Mark A; Xu, Yao; Qin, Ximing; Johnson, Carl Hirschie |
Title: Circadian rhythms of superhelical status of DNA in cyanobacteria |
Year: 2007 |
Publication: Proceedings of the National Academy of Sciences of the United States of America |
Volume: 104 |
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Keywords: Bioware; Circadian Rhythm; Cyanobacteria; DNA, Bacterial; DNA, Superhelical; Gene Expression Regulation, Bacterial; Light; Plasmids; Promoter Regions, Genetic; pXen-13; Transcription, Genetic |
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Author: Malley, R.; Henneke, P.; Morse, S. C.; Cieslewicz, M. J.; Lipsitch, M.; Thompson, C. M.; Kurt-Jones, E.; Paton, J. C.; Wessels, M. R.; Golenbock, D. T. |
Title: Recognition of pneumolysin by Toll-like receptor 4 confers resistance to pneumococcal infection |
Year: 2003 |
Publication: Proceedings of the National Academy of Sciences of the United States of America |
Volume: 100 |
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Keywords: IVIS, Xenogen, Xen10 |
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Author: Xavier Montet; Jose-Luiz Figueiredo; Herlen Alencar; Vasilis Ntziachristos; Umar Mahmood; Ralph Weissleder |
Title: Tomographic Fluorescence Imaging of Tumor Vascular Volume in Mice |
Year: 2007 |
Publication: Radiology |
Volume: 242 |
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Keywords: FMT; fluorescence molecular tomography; in vivo imaging; cancer |
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Author: Herlen Alencar, MD; Martin A. Funovics, MD; Jose Figueiredo, MD; Heloisa Sawaya, MD, PhD; Ralph Weissleder, MD, PhD; Umar Mahmood, MD, PhD |
Title: |
Year: 2007 |
Publication: Radiology |
Volume: 244 |
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Keywords: near infrared; near-intrared; in vivo imaging; colonic cancer |
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Author: Herzog, E.; Taruttis, A.; Beziere, N.; Lutich, A. A.; Razansky, D.; Ntziachristos, V. |
Title: Optical imaging of cancer heterogeneity with multispectral optoacoustic tomography |
Year: 2012 |
Publication: Radiology |
Volume: 263 |
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Keywords: Adenocarcinoma/*diagnosis; Animals; Colonic Neoplasms/*diagnosis; Contrast Media/pharmacokinetics; Disease Models, Animal; Female; Fluorescent Dyes/pharmacokinetics; Gold/pharmacokinetics; Image Processing, Computer-Assisted; Indocyanine Green/pharmacokinetics; Mammary Neoplasms, Experimental/*diagnosis; Mice; Nanoparticles; Spectrum Analysis/methods; Tomography, Optical/*methods |
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