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Author: Cheung, R.; Shen, F.; Phillips, J. H.; McGeachy, M. J.; Cua, D. J.; Heyworth, P. G.; Pierce, R. H. |
Title: Activation of MDL-1 (CLEC5A) on immature myeloid cells triggers lethal shock in mice |
Year: 2011 |
Publication: J Clin Invest |
Volume: 121 |
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Keywords: IVIS, RediJect Inflammation Probe, chemiluminescence, XenoLight, Adaptor Proteins, Signal Transducing/metabolism; Animals; Cell Differentiation; Concanavalin A/toxicity; Dengue Hemorrhagic Fever/etiology; Disease Models, Animal; Disease Progression; Female; Humans; Immunity, Innate; Intracellular Signaling Peptides and Proteins/metabolism; Lectins, C-Type/deficiency/genetics/*immunology; Liver/metabolism/pathology; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Immunological; Myeloid Cells/*immunology/pathology; Nitric Oxide/biosynthesis; Nitric Oxide Synthase Type II/metabolism; Nitric Oxide Synthase Type III/metabolism; Phosphatidylinositol 3-Kinases/metabolism; Protein-Tyrosine Kinases/metabolism; Proto-Oncogene Proteins c-akt/metabolism; Receptors, Cell Surface/deficiency/genetics/*immunology; Receptors, Immunologic/metabolism; Shock/*etiology/*immunology/metabolism/pathology; Signal Transduction; Systemic Inflammatory Response; Syndrome/etiology/immunology/metabolism/pathology; Tumor Necrosis Factor-alpha/biosynthesis |
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Author: Hanai, J.; Doro, N.; Sasaki, A. T.; Kobayashi, S.; Cantley, L. C.; Seth, P.; Sukhatme, V. P. |
Title: Inhibition of lung cancer growth: ATP citrate lyase knockdown and statin treatment leads to dual blockade of mitogen-activated protein kinase (MAPK) and phosphatidylinositol-3-kinase (PI3K)/AKT pathways |
Year: 2012 |
Publication: J Cell Physiol |
Volume: 227 |
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Keywords: A549-luc-C8, A549-luc, IVIS, Bioware, ATP Citrate (pro-S)-Lyase/*antagonists & inhibitors/genetics; Animals; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Combined Modality Therapy; Epithelial-Mesenchymal Transition; Female; Gene Knockdown Techniques; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors/*therapeutic use; Lung Neoplasms/*drug therapy/enzymology/pathology/*therapy; MAP Kinase Signaling System/drug effects; Mice; Mutation; Phosphatidylinositol 3-Kinases/antagonists & inhibitors; Proto-Oncogene Proteins c-akt/antagonists & inhibitors; Receptor, Epidermal Growth Factor/genetics; Signal Transduction/drug effects; Xenograft Model Antitumor Assays |
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Author: Xu, D.; Takeshita, F.; Hino, Y.; Fukunaga, S.; Kudo, Y.; Tamaki, A.; Matsunaga, J.; Takahashi, R. U.; Takata, T.; Shimamoto, A.; Ochiya, T.; Tahara, H. |
Title: miR-22 represses cancer progression by inducing cellular senescence |
Year: 2011 |
Publication: J Cell Biol |
Volume: 193 |
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Keywords: MDA-MB-231-D3H2Ln, IVIS, Bioluminescence |
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Author: Chantry, A. D.; Heath, D.; Mulivor, A. W.; Pearsall, S.; Baud'huin, M.; Coulton, L.; Evans, H.; Abdul, N.; Werner, E. D.; Bouxsein, M. L.; Key, M. L.; Seehra, J.; Arnett, T. R.; Vanderkerken, K.; Croucher, P. |
Title: Inhibiting activin-A signaling stimulates bone formation and prevents cancer-induced bone destruction in vivo |
Year: 2010 |
Publication: J Bone Miner Res |
Volume: 25 |
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Keywords: MDA-MB-231-D3H2Ln, IVIS, Bioluminescence, Activins/*metabolism; Animals; Bone Neoplasms/*complications/pathology/physiopathology/secondary; Bone Resorption/*etiology/pathology/physiopathology/*prevention & control; Calcification, Physiologic/drug effects; Cell Line, Tumor; HEK293 Cells; Humans; Mice; Multiple Myeloma/complications/pathology/physiopathology; Neoplasm Transplantation; Organ Size/drug effects; Osteoblasts/drug effects/pathology; *Osteogenesis/drug effects; Osteolysis/blood/complications/physiopathology/prevention & control; Paraproteins/metabolism; Recombinant Fusion Proteins/pharmacology; *Signal Transduction/drug effects; Survival Analysis; Tumor Burden/drug effects |
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Author: Sabbagh, Y.; Graciolli, F. G.; O'Brien, S.; Tang, W.; dos Reis, L. M.; Ryan, S.; Phillips, L.; Boulanger, J.; Song, W.; Bracken, C.; Liu, S.; Ledbetter, S.; Dechow, P.; Canziani, M. E.; Carvalho, A. B.; Jorgetti, V.; Moyses, R. M.; Schiavi, S. C. |
Title: Repression of osteocyte Wnt/beta-catenin signaling is an early event in the progression of renal osteodystrophy |
Year: 2012 |
Publication: J Bone Miner Res |
Volume: 27 |
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Keywords: OsteoSense, Animals; Biopsy; Bone Remodeling; Bone and Bones/metabolism/pathology; Calcification, Physiologic; Cardiovascular Abnormalities/blood/complications/pathology/physiopathology; *Disease Progression; Female; Gene Expression Profiling; Gene Expression Regulation; Glycoproteins/metabolism; Humans; Kidney Failure, Chronic/blood/complications/pathology/physiopathology; Male; Mice; Mice, Inbred C57BL; Middle Aged; Mutation/genetics; Osteoclasts/metabolism/pathology; Osteocytes/*metabolism/*pathology; Protein-Serine-Threonine Kinases/genetics; Renal Osteodystrophy/blood/*metabolism/*pathology/physiopathology; Vascular Calcification; *Wnt Signaling Pathway/genetics |
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Author: Penn-Barwell, J. G.; Murray, C. K.; Wenke, J. C. |
Title: Early antibiotics and debridement independently reduce infection in an open fracture model |
Year: 2012 |
Publication: J Bone Joint Surg Br |
Volume: 94 |
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Keywords: Xen36, Xen 36, Staphylococcus aureus Xen36, IVIS |
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Author: Tekabe, Y.; Klose, A.; Nizami, S.; Luma, J.; Lee, F. Y.; Johnson, L. |
Title: New application of optical agent to image angiogenesis in hindlimb ischemia |
Year: 2011 |
Publication: J Biophotonics |
Volume: 4 |
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Keywords: IntegriSense, Animals; Antigens, CD31/metabolism; Capillaries/metabolism; Diagnostic Imaging/*methods; Femoral Artery/surgery; Fluorescent Dyes/*diagnostic use/metabolism; Hindlimb/*blood supply/metabolism/pathology; Integrin alphaV/metabolism; Integrin alphaVbeta3/antagonists & inhibitors/metabolism; Ischemia/*pathology; Ligation; Male; Mice; Mice, Inbred Strains; Microscopy, Fluorescence; *Neovascularization, Physiologic; Plant Lectins/metabolism; Sensitivity and Specificity |
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Author: Weljie, A. M.; Bondareva, A.; Zang, P.; Jirik, F. R. |
Title: (1)H NMR metabolomics identification of markers of hypoxia-induced metabolic shifts in a breast cancer model system |
Year: 2011 |
Publication: J Biomol NMR |
Volume: 49 |
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Keywords: MDA-MB-231-luc2, IVIS, Breast Cancer, Bioware |
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Author: Engelsman, A. F.; Mei, H. C. van der; Francis, K. P.; Busscher, H. J.; Ploeg, R. J.; Dam, G. M. van |
Title: Real time noninvasive monitoring of contaminating bacteria in a soft tissue implant infection model |
Year: 2009 |
Publication: J Biomed Mater Res B Appl Biomater |
Volume: 88 |
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Keywords: Bioware; IVIS, Xenogen; Xen29 |
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Author: Arima, Y.; Hayashi, H.; Sasaki, M.; Hosonaga, M.; Goto, T. M.; Chiyoda, T.; Kuninaka, S.; Shibata, T.; Ohata, H.; Nakagama, H.; Taya, Y.; Saya, H. |
Title: Induction of ZEB by inactivation of RB is a key determinant of the mesenchymal phenotype of breast cancer |
Year: 2012 |
Publication: J Biol Chem |
Volume: |
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Keywords: MDA-MB-231-D3H2Ln, IVIS, Bioluminescence |
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