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Author: Kozloff, K. M.; Quinti, L.; Patntirapong, S.; Hauschka, P. V.; Tung, C. H.; Weissleder, R.; Mahmood, U. |
Title: Non-invasive optical detection of cathepsin K-mediated fluorescence reveals osteoclast activity in vitro and in vivo |
Year: 2009 |
Publication: Bone |
Volume: 44 |
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Keywords: OsteoSense, IVIS Animals; Animals, Newborn; Bone Development; Bone Resorption/enzymology; Calcification, Physiologic; Cathepsin K; Cathepsins/genetics/*metabolism; Cell Survival; Cells, Cultured; Cryoultramicrotomy; Female; Femur/pathology; Fluorescence; Humans; Mice; Mice, Inbred BALB C; *Molecular Probe Techniques; Molecular Probes/metabolism; Osteoclasts/cytology/*enzymology; Ovariectomy; RNA, Messenger/genetics/metabolism; Up-Regulation |
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Author: Chen, Y.; Jacamo, R.; Shi, Y. X.; Wang, R. Y.; Battula, V. L.; Konoplev, S.; Strunk, D.; Hofmann, N. A.; Reinisch, A.; Konopleva, M.; Andreeff, M. |
Title: Human extramedullary bone marrow in mice: a novel in vivo model of genetically controlled hematopoietic microenvironment |
Year: 2012 |
Publication: Blood |
Volume: 119 |
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Keywords: OsteoSense, IVIS, Animals; Bone Marrow Cells/*cytology/metabolism/physiology; Bone Marrow Transplantation/*methods/physiology; Cells, Cultured; Cellular Microenvironment/genetics/*physiology; Hematopoiesis, Extramedullary/genetics/*physiology; Humans; Hypoxia-Inducible Factor 1, alpha Subunit/genetics/metabolism; Interleukin Receptor Common gamma Subunit/genetics; Mice; Mice, Inbred NOD; Mice, SCID; Mice, Transgenic; Models, Animal; Osteogenesis/genetics/physiology; Species Specificity; *Transplantation, Heterotopic |
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Author: Wen, D.; Qing, L.; Harrison, G.; Golub, E.; Akintoye, S. O. |
Title: Anatomic site variability in rat skeletal uptake and desorption of fluorescently labeled bisphosphonate |
Year: 2011 |
Publication: Oral Dis |
Volume: 17 |
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Keywords: OsteoSense, Maestro, Animals; Bone Density Conservation Agents/administration & dosage/*pharmacokinetics; Bone and Bones/*metabolism; Calcium/metabolism; Chelating Agents; Decalcification Technique; Diphosphonates/administration & dosage/*pharmacokinetics; Durapatite/metabolism; Edetic Acid; Female; Femur/metabolism; Fibula/metabolism; Fluorescent Dyes/diagnostic use; Fluorometry; Humerus/metabolism; Injections, Intravenous; Mandible/metabolism; Models, Animal; Radius/metabolism; Rats; Rats, Nude; Spectrophotometry, Atomic; Tibia/metabolism; Tissue Distribution; Ulna/metabolism |
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Author: Nakayama, H.; Kawase, T.; Okuda, K.; Wolff, L. F.; Yoshie, H. |
Title: In-vivo near-infrared optical imaging of growing osteosarcoma cell lesions xenografted in mice: dual-channel quantitative evaluation of volume and mineralization |
Year: 2011 |
Publication: Acta Radiol |
Volume: 52 |
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Keywords: OsteoSense,, Animals; Bone Neoplasms/*pathology/physiopathology; Calcification, Physiologic/*physiology; Diphosphonates/diagnostic use; Feasibility Studies; Inositol/analogs & derivatives/diagnostic use; Mice; Mice, Hairless; Osteosarcoma/*pathology/physiopathology; Radiopharmaceuticals/diagnostic use; Spectroscopy, Near-Infrared/*methods; Technetium Tc 99m Medronate/analogs & derivatives/diagnostic use; Transplantation, Heterologous |
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Author: Figueiredo JL, Passerotti CC, Sponholtz T, Nguyen HT and Weissleder R |
Title: A Novel Method of Imaging Calcium Urolithiasis Using Fluorescence |
Year: 2008 |
Publication: The Journal of Urology |
Volume: 179 |
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Keywords: OsteoSense; in vivo imaging; urinary calculi; molecular probes; fluorescence; diagnostic imaging; mice |
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Author: Rahul Anil Sheth; Rabi Upadhyay; Lars Stangenberg; Rucha Sheth; Ralph Weissleder; Umar Mahmood |
Title: Improved detection of ovarian cancer metastases by intraoperative quantitative fluorescence protease imaging in a pre-clinical model |
Year: 2009 |
Publication: Gynecologic Oncology |
Volume: 112 |
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Keywords: Ovarian cancer; Molecular imaging; Intraoperative imaging; Fluorescence imaging |
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Author: |
Title: Highly sensitive detection of early-stage pancreatic cancer by multimodal near-infrared molecular imaging in living mice |
Year: 2008 |
Publication: International Journal of Cancer |
Volume: 123 |
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Keywords: pancreatic cancer; matrix metalloproteinases; near-infrared fluorescence; bioluminescence imaging; detection; in vivo imaging |
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Author: Domanska, U. M.; Timmer-Bosscha, H.; Nagengast, W. B.; Oude Munnink, T. H.; Kruizinga, R. C.; Ananias, H. J.; Kliphuis, N. M.; Huls, G.; De Vries, E. G.; de Jong, I. J.; Walenkamp, A. M. |
Title: CXCR4 inhibition with AMD3100 sensitizes prostate cancer to docetaxel chemotherapy |
Year: 2012 |
Publication: Neoplasia |
Volume: 14 |
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Keywords: PC-3-luc2, Prostate Cancer, Bioware, IVIS |
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Author: Kosaka, N.; Iguchi, H.; Yoshioka, Y.; Hagiwara, K.; Takeshita, F.; Ochiya, T. |
Title: Competitive Interactions of Cancer Cells and Normal Cells via Secretory MicroRNAs |
Year: 2012 |
Publication: J Biol Chem |
Volume: 287 |
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Keywords: PC-3M-luc-C6, PC-3M-luc, IVIS, Bioware, Prostate cancer, Bioluminescence |
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Author: Ru, P.; Steele, R.; Newhall, P.; Phillips, N. J.; Toth, K.; Ray, R. B. |
Title: miRNA-29b suppresses prostate cancer metastasis by regulating epithelial-mesenchymal transition signaling |
Year: 2012 |
Publication: Mol Cancer Ther |
Volume: 11 |
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Keywords: PC-3M-luc-C6, PC-3M-luc, IVIS, Bioware, Prostate cancer, Bioluminescence |
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