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Author: Kozloff, K. M.; Quinti, L.; Patntirapong, S.; Hauschka, P. V.; Tung, C. H.; Weissleder, R.; Mahmood, U. | Title: Non-invasive optical detection of cathepsin K-mediated fluorescence reveals osteoclast activity in vitro and in vivo | Year: 2009 | Publication: Bone | Volume: 44 | Products: | Keywords: OsteoSense, IVIS Animals; Animals, Newborn; Bone Development; Bone Resorption/enzymology; Calcification, Physiologic; Cathepsin K; Cathepsins/genetics/*metabolism; Cell Survival; Cells, Cultured; Cryoultramicrotomy; Female; Femur/pathology; Fluorescence; Humans; Mice; Mice, Inbred BALB C; *Molecular Probe Techniques; Molecular Probes/metabolism; Osteoclasts/cytology/*enzymology; Ovariectomy; RNA, Messenger/genetics/metabolism; Up-Regulation |
Author: Chen, Y.; Jacamo, R.; Shi, Y. X.; Wang, R. Y.; Battula, V. L.; Konoplev, S.; Strunk, D.; Hofmann, N. A.; Reinisch, A.; Konopleva, M.; Andreeff, M. | Title: Human extramedullary bone marrow in mice: a novel in vivo model of genetically controlled hematopoietic microenvironment | Year: 2012 | Publication: Blood | Volume: 119 | Products: | Keywords: OsteoSense, IVIS, Animals; Bone Marrow Cells/*cytology/metabolism/physiology; Bone Marrow Transplantation/*methods/physiology; Cells, Cultured; Cellular Microenvironment/genetics/*physiology; Hematopoiesis, Extramedullary/genetics/*physiology; Humans; Hypoxia-Inducible Factor 1, alpha Subunit/genetics/metabolism; Interleukin Receptor Common gamma Subunit/genetics; Mice; Mice, Inbred NOD; Mice, SCID; Mice, Transgenic; Models, Animal; Osteogenesis/genetics/physiology; Species Specificity; *Transplantation, Heterotopic |
Author: Wen, D.; Qing, L.; Harrison, G.; Golub, E.; Akintoye, S. O. | Title: Anatomic site variability in rat skeletal uptake and desorption of fluorescently labeled bisphosphonate | Year: 2011 | Publication: Oral Dis | Volume: 17 | Products: | Keywords: OsteoSense, Maestro, Animals; Bone Density Conservation Agents/administration & dosage/*pharmacokinetics; Bone and Bones/*metabolism; Calcium/metabolism; Chelating Agents; Decalcification Technique; Diphosphonates/administration & dosage/*pharmacokinetics; Durapatite/metabolism; Edetic Acid; Female; Femur/metabolism; Fibula/metabolism; Fluorescent Dyes/diagnostic use; Fluorometry; Humerus/metabolism; Injections, Intravenous; Mandible/metabolism; Models, Animal; Radius/metabolism; Rats; Rats, Nude; Spectrophotometry, Atomic; Tibia/metabolism; Tissue Distribution; Ulna/metabolism |
Author: Nakayama, H.; Kawase, T.; Okuda, K.; Wolff, L. F.; Yoshie, H. | Title: In-vivo near-infrared optical imaging of growing osteosarcoma cell lesions xenografted in mice: dual-channel quantitative evaluation of volume and mineralization | Year: 2011 | Publication: Acta Radiol | Volume: 52 | Products: | Keywords: OsteoSense,, Animals; Bone Neoplasms/*pathology/physiopathology; Calcification, Physiologic/*physiology; Diphosphonates/diagnostic use; Feasibility Studies; Inositol/analogs & derivatives/diagnostic use; Mice; Mice, Hairless; Osteosarcoma/*pathology/physiopathology; Radiopharmaceuticals/diagnostic use; Spectroscopy, Near-Infrared/*methods; Technetium Tc 99m Medronate/analogs & derivatives/diagnostic use; Transplantation, Heterologous |
Author: Figueiredo JL, Passerotti CC, Sponholtz T, Nguyen HT and Weissleder R | Title: A Novel Method of Imaging Calcium Urolithiasis Using Fluorescence | Year: 2008 | Publication: The Journal of Urology | Volume: 179 | Products: | Keywords: OsteoSense; in vivo imaging; urinary calculi; molecular probes; fluorescence; diagnostic imaging; mice |
Author: Rahul Anil Sheth; Rabi Upadhyay; Lars Stangenberg; Rucha Sheth; Ralph Weissleder; Umar Mahmood | Title: Improved detection of ovarian cancer metastases by intraoperative quantitative fluorescence protease imaging in a pre-clinical model | Year: 2009 | Publication: Gynecologic Oncology | Volume: 112 | Products: | Keywords: Ovarian cancer; Molecular imaging; Intraoperative imaging; Fluorescence imaging |
Author: | Title: Highly sensitive detection of early-stage pancreatic cancer by multimodal near-infrared molecular imaging in living mice | Year: 2008 | Publication: International Journal of Cancer | Volume: 123 | Products: | Keywords: pancreatic cancer; matrix metalloproteinases; near-infrared fluorescence; bioluminescence imaging; detection; in vivo imaging |
Author: Domanska, U. M.; Timmer-Bosscha, H.; Nagengast, W. B.; Oude Munnink, T. H.; Kruizinga, R. C.; Ananias, H. J.; Kliphuis, N. M.; Huls, G.; De Vries, E. G.; de Jong, I. J.; Walenkamp, A. M. | Title: CXCR4 inhibition with AMD3100 sensitizes prostate cancer to docetaxel chemotherapy | Year: 2012 | Publication: Neoplasia | Volume: 14 | Products: | Keywords: PC-3-luc2, Prostate Cancer, Bioware, IVIS |
Author: Kosaka, N.; Iguchi, H.; Yoshioka, Y.; Hagiwara, K.; Takeshita, F.; Ochiya, T. | Title: Competitive Interactions of Cancer Cells and Normal Cells via Secretory MicroRNAs | Year: 2012 | Publication: J Biol Chem | Volume: 287 | Products: | Keywords: PC-3M-luc-C6, PC-3M-luc, IVIS, Bioware, Prostate cancer, Bioluminescence |
Author: Ru, P.; Steele, R.; Newhall, P.; Phillips, N. J.; Toth, K.; Ray, R. B. | Title: miRNA-29b suppresses prostate cancer metastasis by regulating epithelial-mesenchymal transition signaling | Year: 2012 | Publication: Mol Cancer Ther | Volume: 11 | Products: | Keywords: PC-3M-luc-C6, PC-3M-luc, IVIS, Bioware, Prostate cancer, Bioluminescence |