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  Author   Title   Year   Publication   Volume   Products   Keywords   Links  
Author: Stan, Silvia D; Hahm, Eun-Ryeong; Warin, Renaud; Singh, Shivendra V Title: Withaferin A causes FOXO3a- and Bim-dependent apoptosis and inhibits growth of human breast cancer cells in vivo Year: 2008 Publication: Cancer research Volume: 68 Products: Keywords: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Bioware; Breast Neoplasms; Cell Growth Processes; Cell Line, Tumor; Ergosterol; Female; Forkhead Transcription Factors; Humans; MDA-MB-231-D3H1 cells; Membrane Proteins; Mice; Mice, Nude; Proto-Oncogene Proteins; RNA, Small Interfering; Transfection; Withanolides; Xenograft Model Antitumor Assays details  
Author: Shimomura, Toshiyasu; Hasako, Shinichi; Nakatsuru, Yoko; Mita, Takashi; Ichikawa, Koji; Kodera, Tsutomu; Sakai, Takumi; Nambu, Tadahiro; Miyamoto, Mayu; Takahashi, Ikuko; Miki, Satomi; Kawanishi, Nobuhiko; Ohkubo, Mitsuru; Kotani, Hidehito; Iwasawa, Yoshikazu Title: MK-5108, a highly selective Aurora-A kinase inhibitor, shows antitumor activity alone and in combination with docetaxel Year: 2010 Publication: Molecular cancer therapeutics Volume: 9 Products: Keywords: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bioware; Cell Death; Cell Line, Tumor; Cell Proliferation; Cyclohexanecarboxylic Acids; HeLa-luc; Humans; Inhibitory Concentration 50; Mice; Mitosis; Protein kinase inhibitors; Protein-Serine-Threonine Kinases; Rats; Taxoids; Thiazoles; Xenograft Model Antitumor Assays details  
Author: Sharma, Praveen K; Singh, Rajesh; Novakovic, Kristian R; Eaton, John W; Grizzle, William E; Singh, Shailesh Title: CCR9 mediates PI3K/AKT-dependent antiapoptotic signals in prostate cancer cells and inhibition of CCR9-CCL25 interaction enhances the cytotoxic effects of etoposide Year: 2010 Publication: International journal of cancer. Journal international du cancer Volume: 127 Products: Keywords: Animals; Antineoplastic Agents; Apoptosis; Bioware; Caspase 3; Cell Line, Tumor; Chemokines, CC; Disease Progression; Enzyme Activation; Etoposide; Humans; Male; Mice; Mice, Nude; PC-3M-luc; Phosphatidylinositol 3-Kinases; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Receptors, CCR; Signal Transduction details  
Author: Hickson, J; Ackler, S; Klaubert, D; Bouska, J; Ellis, P; Foster, K; Oleksijew, A; Rodriguez, L; Schlessinger, S; Wang, B; Frost, D Title: Noninvasive molecular imaging of apoptosis in vivo using a modified firefly luciferase substrate, Z-DEVD-aminoluciferin Year: 2010 Publication: Cell death and differentiation Volume: 17 Products: Keywords: Animals; Antineoplastic Agents; Apoptosis; Bioware; Caspase 3; Cell Line, Tumor; Female; Firefly Luciferin; Humans; Luminescent Agents; MDA-MB-231-D3H2LN cells; Mice; Mice, SCID; SKOV3-luc-D3 cells; Molecular Imaging; Neoplasms; Oligopeptides; Taxoids details  
Author: Smith, Eric L; Schuchman, Edward H Title: Acid sphingomyelinase overexpression enhances the antineoplastic effects of irradiation in vitro and in vivo Year: 2008 Publication: Molecular therapy: the journal of the American Society of Gene Therapy Volume: 16 Products: Keywords: Animals; Antineoplastic Agents; Autophagy; B16-F10-luc-G5 cells; Bioware; Cell Survival; Cells, Cultured; Ceramides; Cesium Radioisotopes; CHO Cells; Combined Modality Therapy; Cricetinae; Cricetulus; Endothelium, Vascular; Female; Gamma Rays; Gene Expression Regulation, Enzymologic; Gene Therapy; Humans; Melanoma, Experimental; Mice; Sphingomyelin Phosphodiesterase details  
Author: Holland, Sacha J; Pan, Alison; Franci, Christian; Hu, Yuanming; Chang, Betty; Li, Weiqun; Duan, Matt; Torneros, Allan; Yu, Jiaxin; Heckrodt, Thilo J; Zhang, Jing; Ding, Pingyu; Apatira, Ayodele; Chua, Joanne; Brandt, Ralf; Pine, Polly; Goff, Dane; Singh, Rajinder; Payan, Donald G; Hitoshi, Yasumichi Title: R428, a selective small molecule inhibitor of Axl kinase, blocks tumor spread and prolongs survival in models of metastatic breast cancer Year: 2010 Publication: Cancer research Volume: 70 Products: Keywords: Animals; Antineoplastic Agents; Benzocycloheptenes; Bioware; Breast Neoplasms; Carcinoma; Female; Hela Cells; Humans; K562 Cells; MDA-MB-231-D3H2LN cells; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Oncogene Proteins; Protein kinase inhibitors; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Survival Analysis; Triazoles; Tumor Cells, Cultured; Xenograft Model Antitumor Assays details  
Author: Ranganath, Sudhir H; Fu, Yilong; Arifin, Davis Y; Kee, Irene; Zheng, Lin; Lee, How-Sung; Chow, Pierce K-H; Wang, Chi-Hwa Title: The use of submicron/nanoscale PLGA implants to deliver paclitaxel with enhanced pharmacokinetics and therapeutic efficacy in intracranial glioblastoma in mice Year: 2010 Publication: Biomaterials Volume: 31 Products: Keywords: Animals; Antineoplastic Agents; Bioware; Brain Neoplasms; Cell Line, Tumor; Drug Implants; Glioblastoma; Male; Metabolic Clearance Rate; Mice; Mice, Inbred BALB C; Nanostructures; Paclitaxel; Treatment Outcome; U-87 MG-luc2 details  
Author: Jenkins, Darlene E; Yu, Shang-Fan; Hornig, Yvette S; Purchio, Tony; Contag, Pamela R Title: In vivo monitoring of tumor relapse and metastasis using bioluminescent PC-3M-luc-C6 cells in murine models of human prostate cancer Year: 2003 Publication: Clinical & experimental metastasis Volume: 20 Products: Keywords: Animals; Antineoplastic Agents; Bioware; Cell Line, Tumor; Disease Models, Animal; Heart Neoplasms; Humans; Injections, Subcutaneous; Luminescent Measurements; Lung Neoplasms; Lymphatic Metastasis; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Recurrence, Local; PC-3M-luc; Prostatic Neoplasms details  
Author: Cabral, Horacio; Nishiyama, Nobuhiro; Kataoka, Kazunori Title: Optimization of (1,2-diamino-cyclohexane)platinum(II)-loaded polymeric micelles directed to improved tumor targeting and enhanced antitumor activity Year: 2007 Publication: Journal of controlled release: official journal of the Controlled Release Society Volume: 121 Products: Keywords: Animals; Antineoplastic Agents; Bioware; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Female; Hela Cells; HeLa-luc; Humans; Mice; Mice, SCID; Micelles; Neoplasms; Organoplatinum Compounds; Platinum; Polymers; Xenograft Model Antitumor Assays details  
Author: Zhang, H-Y; Man, J-H; Liang, B; Zhou, T; Wang, C-H; Li, T; Li, H-Y; Li, W-H; Jin, B-F; Zhang, P-J; Zhao, J; Pan, X; He, K; Gong, W-L; Zhang, X-M; Li, A-L Title: Tumor-targeted delivery of biologically active TRAIL protein Year: 2010 Publication: Cancer gene therapy Volume: 17 Products: Keywords: Animals; Apoptosis; B16-F10-luc-G5 cells; Bioware; Blotting, Western; Cell Line, Tumor; Escherichia coli; Female; Flow Cytometry; Gene Therapy; Genetic Vectors; Humans; Immunohistochemistry; Mice; Mice, Inbred BALB C; Mice, Nude; NCI-H460-luc2; Neoplasms; Polymerase Chain Reaction; Survival Rate; TNF-Related Apoptosis-Inducing Ligand details