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Author: Inglefield, Jon R; Dumitru, Calin Dan; Alkan, Sefik S; Gibson, Sheila J; Lipson, Kenneth E; Tomai, Mark A; Larson, Chris J; Vasilakos, John P |
Title: TLR7 agonist 852A inhibition of tumor cell proliferation is dependent on plasmacytoid dendritic cells and type I IFN |
Year: 2008 |
Publication: Journal of interferon & cytokine research: the official journal of the International Society for Interferon and Cytokine Research |
Volume: 28 |
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Keywords: Aminoquinolines; Animals; B16-F10-luc-G5 cells; Bioware; Cell Line, Tumor; Cell Proliferation; Cell Survival; Culture Media, Conditioned; dendritic cells; Humans; Interferon Type I; Leukocytes, Mononuclear; Lung; Melanoma; Mice; Neoplasms; Oligodeoxyribonucleotides; Quinolines; Subcellular Fractions; Sulfonamides; Toll-Like Receptor 7 |
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Author: Bisland, Stuart K; Chien, Claudia; Wilson, Brian C; Burch, Shane |
Title: Pre-clinical in vitro and in vivo studies to examine the potential use of photodynamic therapy in the treatment of osteomyelitis |
Year: 2006 |
Publication: Photochemical & photobiological sciences: Official journal of the European Photochemistry Association and the European Society for Photobiology |
Volume: 5 |
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Keywords: Aminolevulinic Acid; Animals; Biofilms; Bioware; Cell Survival; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Implants, Experimental; Light; Luminescent Measurements; Methylene Blue; Osteomyelitis; Photochemotherapy; Photosensitizing Agents; Rats; Rats, Sprague-Dawley; Staphylococcus aureus; Xen29 |
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Author: Schwan, William R; Lehmann, Lynn; McCormick, James |
Title: Transcriptional activation of the Staphylococcus aureus putP gene by low-proline-high osmotic conditions and during infection of murine and human tissues |
Year: 2006 |
Publication: Infection and immunity |
Volume: 74 |
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Keywords: Amino Acid Transport Systems, Neutral; Animals; Bacterial Proteins; Bioware; Blotting, Northern; Disease Models, Animal; Gene Expression Regulation, Bacterial; Humans; Lac Operon; Mice; Osmolar Concentration; Proline; pXen-5; Recombinant Fusion Proteins; Staphylococcal Infections; Staphylococcus aureus; Symporters; Transcriptional Activation |
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Author: Rambow-Larsen, Amy A; Rajashekara, Gireesh; Petersen, Erik; Splitter, Gary |
Title: Putative quorum-sensing regulator BlxR of Brucella melitensis regulates virulence factors including the type IV secretion system and flagella |
Year: 2008 |
Publication: Journal of bacteriology |
Volume: 190 |
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Keywords: Amino Acid Sequence; Animals; Bioware; Brucella melitensis; Brucellosis; Disease Models, Animal; Flagella; Gene Deletion; Gene Expression Regulation, Bacterial; Interferon Regulatory Factor-1; Macrophages; Mice; Mice, Mutant Strains; Molecular Sequence Data; Oligonucleotide Array Sequence Analysis; pXen-13; Quorum Sensing; Repressor Proteins; Trans-Activators; Virulence Factors |
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Author: |
Title: Synthetic cationic peptide IDR-1002 provides protection against bacterial infections through chemokine induction and enhanced leukocyte recruitment |
Year: 2010 |
Publication: Journal of immunology (Baltimore, Md.: 1950) |
Volume: 184 |
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Keywords: Amino Acid Sequence; Animals; Antimicrobial Cationic Peptides; Bacterial Infections; Bioware; Cell Line; Cells, Cultured; Chemokine CCL2; Chemokine CCL7; Chemokine CXCL1; Chemokines; Female; Humans; Interleukin-8; Leukocytes; Leukocytes, Mononuclear; Macrophages; Mice; Mice, Inbred C57BL; Molecular Sequence Data; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Staphylococcal Infections; Staphylococcus aureus; Xen29, Xen14 |
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Author: Srivastava, Amit; Henneke, Philipp; Visintin, Alberto; Morse, Sarah C; Martin, Victoria; Watkins, Claire; Paton, James C; Wessels, Michael R; Golenbock, Douglas T; Malley, Richard |
Title: The apoptotic response to pneumolysin is Toll-like receptor 4 dependent and protects against pneumococcal disease |
Year: 2005 |
Publication: Infection and immunity |
Volume: 73 |
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Keywords: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Bacterial Proteins; Caspases; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred Strains; Nasopharynx; Pneumococcal Infections; Streptococcus pneumoniae; Streptolysins; Xen10 |
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Author: |
Title: VAP-1-deficient mice display defects in mucosal immunity and antimicrobial responses: implications for antiadhesive applications |
Year: 2007 |
Publication: Journal of immunology (Baltimore, Md.: 1950) |
Volume: 179 |
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Keywords: Amine Oxidase (Copper-Containing); Animals; Bacterial Adhesion; Bioware; Cell Adhesion Molecules; Coxsackievirus Infections; Immunity, Mucosal; Immunoglobulin A; Lymphocyte Count; Lymphocytes; Lymphoid Tissue; Mice; Mice, Inbred C57BL; Mice, Knockout; Peyer's Patches; Receptors, Lymphocyte Homing; Staphylococcal Vaccines; Staphylococcus aureus; Xen36 |
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Author: Marttila-Ichihara, Fumiko; Auvinen, Kaisa; Elima, Kati; Jalkanen, Sirpa; Salmi, Marko |
Title: Vascular adhesion protein-1 enhances tumor growth by supporting recruitment of Gr-1+CD11b+ myeloid cells into tumors |
Year: 2009 |
Publication: Cancer research |
Volume: 69 |
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Keywords: Amine Oxidase (Copper-Containing); Animals; Antigens, CD11b; B16-F10-luc-G5 cells; Bioware; Cell Adhesion Molecules; Cell Growth Processes; Female; Lymphoma; Male; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myeloid Cells; Neovascularization, Pathologic; Oxidoreductases; Receptors, Chemokine |
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Author: Hu, Guohong; Chong, Robert A; Yang, Qifeng; Wei, Yong; Blanco, Mario A; Li, Feng; Reiss, Michael; Au, Jessie L-S; Haffty, Bruce G; Kang, Yibin |
Title: MTDH activation by 8q22 genomic gain promotes chemoresistance and metastasis of poor-prognosis breast cancer |
Year: 2009 |
Publication: Cancer cell |
Volume: 15 |
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Keywords: Aldehyde Dehydrogenase; Animals; Bioware; Breast Neoplasms; Cell Adhesion Molecules; Cell Line, Tumor; Chromosomes, Human, Pair 8; Drug Resistance, Neoplasm; Gene Expression Profiling; Genome, Human; Humans; MDA-MB-231-D3H2LN cells; Mice; Mice, Nude; Neoplasm Metastasis; Neoplasm Recurrence, Local; Prognosis; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-met; Receptors, Growth Factor; Survival Rate; Xenograft Model Antitumor Assays |
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Author: Xiao, Kai; Luo, Juntao; Fowler, Wiley L; Li, Yuanpei; Lee, Joyce S; Xing, Li; Cheng, R Holland; Wang, Li; Lam, Kit S |
Title: A self-assembling nanoparticle for paclitaxel delivery in ovarian cancer |
Year: 2009 |
Publication: Biomaterials |
Volume: 30 |
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Keywords: Albumins; Animals; Antineoplastic Agents; Biocompatible Materials; Bioware; Cell Line, Tumor; Drug Delivery Systems; Emulsifying Agents; Female; Humans; Male; Maximum Tolerated Dose; Mice; Mice, Nude; Nanoparticles; Ovarian Neoplasms; Paclitaxel; Polyethylene Glycols; SKOV3-luc-D3 cells; Spectroscopy, Near-Infrared |