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Author: Hanai, J.; Doro, N.; Sasaki, A. T.; Kobayashi, S.; Cantley, L. C.; Seth, P.; Sukhatme, V. P. |
Title: Inhibition of lung cancer growth: ATP citrate lyase knockdown and statin treatment leads to dual blockade of mitogen-activated protein kinase (MAPK) and phosphatidylinositol-3-kinase (PI3K)/AKT pathways |
Year: 2012 |
Publication: J Cell Physiol |
Volume: 227 |
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Keywords: A549-luc-C8, A549-luc, IVIS, Bioware, ATP Citrate (pro-S)-Lyase/*antagonists & inhibitors/genetics; Animals; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Combined Modality Therapy; Epithelial-Mesenchymal Transition; Female; Gene Knockdown Techniques; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors/*therapeutic use; Lung Neoplasms/*drug therapy/enzymology/pathology/*therapy; MAP Kinase Signaling System/drug effects; Mice; Mutation; Phosphatidylinositol 3-Kinases/antagonists & inhibitors; Proto-Oncogene Proteins c-akt/antagonists & inhibitors; Receptor, Epidermal Growth Factor/genetics; Signal Transduction/drug effects; Xenograft Model Antitumor Assays |
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Author: Joh, E. H.; Hollenbaugh, J. A.; Kim, B.; Kim, D. H. |
Title: Pleckstrin homology domain of akt kinase: a proof of principle for highly specific and effective non-enzymatic anti-cancer target |
Year: 2012 |
Publication: PLoS One |
Volume: 7 |
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Keywords: A549-luc-C8, A549-luc, IVIS, Bioware |
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Author: Johnson, J. L.; Pillai, S.; Pernazza, D.; Sebti, S. M.; Lawrence, N. J.; Chellappan, S. P. |
Title: Regulation of matrix metalloproteinase genes by E2F transcription factors: Rb-Raf-1 interaction as a novel target for metastatic disease |
Year: 2012 |
Publication: Cancer Res |
Volume: 72 |
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Keywords: A549-luc-C8, A549-luc, IVIS, Bioware, Animals; Breast Neoplasms/genetics/metabolism/pathology; Carcinoma, Non-Small-Cell Lung/genetics/metabolism/pathology; Cell Line, Tumor; E2F Transcription Factors/*genetics/metabolism; Enzyme Assays/methods; Female; Gelatin/metabolism; *Gene Expression Regulation, Enzymologic; *Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms/genetics/metabolism/pathology; Matrix Metalloproteinases/biosynthesis/*genetics/metabolism; Mice; Mice, SCID; Neoplasm Metastasis; Phosphatidylethanolamine Binding Protein/*metabolism; Retinoblastoma Protein/genetics/*metabolism; Transcription, Genetic; Transfection |
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Author: Zhuang, H.; Jiang, W.; Zhang, X.; Qiu, F.; Gan, Z.; Cheng, W.; Zhang, J.; Guan, S.; Tang, B.; Huang, Q.; Wu, X.; Huang, X.; Hu, Q.; Lu, M.; Hua, Z. C. |
Title: Suppression of HSP70 expression sensitizes NSCLC cell lines to TRAIL-induced apoptosis by upregulating DR4 and DR5 and downregulating c-FLIP-L expressions |
Year: 2012 |
Publication: J Mol Med (Berl) |
Volume: |
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Keywords: A549-luc-C8, A549-luc, IVIS, Bioware |
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Author: Alsaadi, M.; Italia, J. L.; Mullen, A. B.; Ravi Kumar, M. N.; Candlish, A. A.; Williams, R. A.; Shaw, C. D.; Al Gawhari, F.; Coombs, G. H.; Wiese, M.; Thomson, A. H.; Puig-Sellart, M.; Wallace, J.; Sharp, A.; Wheeler, L.; Warn, P.; Carter, K. C. |
Title: The efficacy of aerosol treatment with non-ionic surfactant vesicles containing amphotericin B in rodent models of leishmaniasis and pulmonary aspergillosis infection |
Year: 2012 |
Publication: J Control Release |
Volume: 160 |
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Keywords: IVIS, B16-F10-luc-G5, B16F10-luc-G5, B16-F10-luc, B16F10-luc, Aerosols; Amphotericin B/*administration & dosage; Animals; Antifungal Agents/*administration & dosage; Cricetinae; Disease Models, Animal; Drug Carriers/*administration & dosage; Female; Firefly Luciferin/administration & dosage; Leishmaniasis/*drug therapy/metabolism/microbiology; Liver/metabolism/microbiology; Lung/metabolism/microbiology; Mesocricetus; Mice; Mice, Inbred BALB C; Pulmonary Aspergillosis/*drug therapy/metabolism/microbiology; Rats; Rats, Sprague-Dawley; Surface-Active Agents/*administration & dosage |
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Author: Carlisle, R.; Seymour, L. W.; Coussios, C. C. |
Title: Targeting of Liposomes via PSGL1 for Enhanced Tumor Accumulation |
Year: 2012 |
Publication: Pharm Res |
Volume: |
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Keywords: IVIS, B16-F10-luc-G5, B16F10-luc-G5, B16-F10-luc, B16F10-luc |
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Author: Close, P.; Gillard, M.; Ladang, A.; Jiang, Z.; Papuga, J.; Hawkes, N.; Nguyen, L.; Chapelle, J. P.; Bouillenne, F.; Svejstrup, J.; Fillet, M.; Chariot, A. |
Title: DERP6 (ELP5) and C3ORF75 (ELP6) regulate tumorigenicity and migration of melanoma cells as subunits of Elongator |
Year: 2012 |
Publication: J Biol Chem |
Volume: 287 |
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Keywords: IVIS, B16-F10-luc-G5, B16F10-luc-G5, B16-F10-luc, B16F10-luc, Carrier Proteins/genetics/*metabolism; Cell Line, Tumor; *Cell Movement; Gene Deletion; HEK293 Cells; Humans; Melanoma/genetics/*metabolism/pathology; Multiprotein Complexes/genetics/*metabolism; Neoplasm Invasiveness; Neoplasm Proteins/genetics/*metabolism; Proteins/genetics/*metabolism; RNA Polymerase II/genetics/metabolism |
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Author: Kim, J. K.; Won, Y. W.; Lim, K. S.; Kim, Y. H. |
Title: Low-molecular-weight methylcellulose-based thermo-reversible gel/pluronic micelle combination system for local and sustained docetaxel delivery |
Year: 2012 |
Publication: Pharm Res |
Volume: 29 |
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Keywords: IVIS, B16-F10-luc-G5, B16F10-luc-G5, B16-F10-luc, B16F10-luc, Animals; Antineoplastic Agents/*administration & dosage/pharmacokinetics/therapeutic use; Delayed-Action Preparations/*chemistry; Male; Methylcellulose/*chemistry; Mice; Mice, Inbred C57BL; *Micelles; Neoplasms/drug therapy; Poloxamer/*chemistry; Taxoids/*administration & dosage/pharmacokinetics/therapeutic use |
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Author: Lemarie, F.; Chang, C. W.; Blatchford, D. R.; Amor, R.; Norris, G.; Tetley, L.; McConnell, G.; Dufes, C. |
Title: Antitumor activity of the tea polyphenol epigallocatechin-3-gallate encapsulated in targeted vesicles after intravenous administration |
Year: 2012 |
Publication: Nanomedicine (Lond) |
Volume: |
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Keywords: IVIS, B16-F10-luc-G5, B16F10-luc-G5, B16-F10-luc, B16F10-luc |
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Author: Matsumoto, A.; Cabral, H.; Sato, N.; Kataoka, K.; Miyahara, Y. |
Title: Assessment of tumor metastasis by the direct determination of cell-membrane sialic acid expression |
Year: 2010 |
Publication: Angew Chem Int Ed Engl |
Volume: 49 |
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Keywords: IVIS, B16-F10-luc-G5, B16F10-luc-G5, B16-F10-luc, B16F10-luc, Animals; Cell Membrane/*pathology; Electrodes; Luminescence; Lung Neoplasms/*secondary; Melanoma/*secondary; Mice; Mice, Inbred BALB C; N-Acetylneuraminic Acid/*metabolism; Potentiometry/methods |
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