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Author: Wallis de Vries, B. M.; Hillebrands, J. L.; van Dam, G. M.; Tio, R. A.; de Jong, J. S.; Slart, R. H.; Zeebregts, C. J. |
Title: Images in cardiovascular medicine. Multispectral near-infrared fluorescence molecular imaging of matrix metalloproteinases in a human carotid plaque using a matrix-degrading metalloproteinase-sensitive activatable fluorescent probe |
Year: 2009 |
Publication: Circulation |
Volume: 119 |
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Keywords: MMPSense, IVIS, Aged; Carotid Artery Diseases/diagnosis/enzymology/*pathology; Diagnostic Imaging/methods; Female; Humans; Matrix Metalloproteinase 9/analysis; Matrix Metalloproteinases/*analysis; Spectroscopy, Near-Infrared/*methods; Tissue Distribution |
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Author: Wallis de Vries, B. M.; van Dam, G. M.; Tio, R. A.; Hillebrands, J. L.; Slart, R. H.; Zeebregts, C. J. |
Title: Current imaging modalities to visualize vulnerability within the atherosclerotic carotid plaque |
Year: 2008 |
Publication: J Vasc Surg |
Volume: 48 |
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Keywords: MMPSense, IVIS, Atherosclerosis/complications/*diagnosis; Carotid Stenosis/*diagnosis/etiology; Diagnostic Imaging/*methods; Humans; Reproducibility of Results |
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Author: Chen, Y.; Jacamo, R.; Shi, Y. X.; Wang, R. Y.; Battula, V. L.; Konoplev, S.; Strunk, D.; Hofmann, N. A.; Reinisch, A.; Konopleva, M.; Andreeff, M. |
Title: Human extramedullary bone marrow in mice: a novel in vivo model of genetically controlled hematopoietic microenvironment |
Year: 2012 |
Publication: Blood |
Volume: 119 |
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Keywords: OsteoSense, IVIS, Animals; Bone Marrow Cells/*cytology/metabolism/physiology; Bone Marrow Transplantation/*methods/physiology; Cells, Cultured; Cellular Microenvironment/genetics/*physiology; Hematopoiesis, Extramedullary/genetics/*physiology; Humans; Hypoxia-Inducible Factor 1, alpha Subunit/genetics/metabolism; Interleukin Receptor Common gamma Subunit/genetics; Mice; Mice, Inbred NOD; Mice, SCID; Mice, Transgenic; Models, Animal; Osteogenesis/genetics/physiology; Species Specificity; *Transplantation, Heterotopic |
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Author: Kozloff, K. M.; Quinti, L.; Patntirapong, S.; Hauschka, P. V.; Tung, C. H.; Weissleder, R.; Mahmood, U. |
Title: Non-invasive optical detection of cathepsin K-mediated fluorescence reveals osteoclast activity in vitro and in vivo |
Year: 2009 |
Publication: Bone |
Volume: 44 |
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Keywords: OsteoSense, IVIS Animals; Animals, Newborn; Bone Development; Bone Resorption/enzymology; Calcification, Physiologic; Cathepsin K; Cathepsins/genetics/*metabolism; Cell Survival; Cells, Cultured; Cryoultramicrotomy; Female; Femur/pathology; Fluorescence; Humans; Mice; Mice, Inbred BALB C; *Molecular Probe Techniques; Molecular Probes/metabolism; Osteoclasts/cytology/*enzymology; Ovariectomy; RNA, Messenger/genetics/metabolism; Up-Regulation |
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Author: Wen, D.; Qing, L.; Harrison, G.; Golub, E.; Akintoye, S. O. |
Title: Anatomic site variability in rat skeletal uptake and desorption of fluorescently labeled bisphosphonate |
Year: 2011 |
Publication: Oral Dis |
Volume: 17 |
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Keywords: OsteoSense, Maestro, Animals; Bone Density Conservation Agents/administration & dosage/*pharmacokinetics; Bone and Bones/*metabolism; Calcium/metabolism; Chelating Agents; Decalcification Technique; Diphosphonates/administration & dosage/*pharmacokinetics; Durapatite/metabolism; Edetic Acid; Female; Femur/metabolism; Fibula/metabolism; Fluorescent Dyes/diagnostic use; Fluorometry; Humerus/metabolism; Injections, Intravenous; Mandible/metabolism; Models, Animal; Radius/metabolism; Rats; Rats, Nude; Spectrophotometry, Atomic; Tibia/metabolism; Tissue Distribution; Ulna/metabolism |
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Author: Ale, A.; Ermolayev, V.; Herzog, E.; Cohrs, C.; de Angelis, M. H.; Ntziachristos, V. |
Title: FMT-XCT: in vivo animal studies with hybrid fluorescence molecular tomography-X-ray computed tomography |
Year: 2012 |
Publication: Nat Methods |
Volume: 9 |
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Keywords: OsteoSense, Animals; Bone Remodeling; Disease Models, Animal; Equipment Design; Female; Fluorescence; Head and Neck Neoplasms/pathology/radiography; Image Processing, Computer-Assisted/*methods; Lung Neoplasms/pathology/radiography; Mammary Neoplasms, Experimental/pathology/radiography; Mice; Osteogenesis Imperfecta/pathology/radiography; Tomography, Optical/*methods; Tomography, X-Ray Computed/*methods |
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Author: Derwall, M.; Malhotra, R.; Lai, C. S.; Beppu, Y.; Aikawa, E.; Seehra, J. S.; Zapol, W. M.; Bloch, K. D.; Yu, P. B. |
Title: Inhibition of bone morphogenetic protein signaling reduces vascular calcification and atherosclerosis |
Year: 2012 |
Publication: Arterioscler Thromb Vasc Biol |
Volume: 32 |
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Keywords: OsteoSense, Animals; Anti-Inflammatory Agents/pharmacology; Antioxidants/pharmacology; Atherosclerosis/etiology/genetics/metabolism/pathology/*prevention & control; Bone Morphogenetic Protein Receptors, Type I/metabolism; Bone Morphogenetic Proteins/*antagonists & inhibitors/metabolism; Cardiovascular Agents/*pharmacology; Cholesterol, LDL/blood; Diet, High-Fat; Disease Models, Animal; Endothelial Cells/drug effects/metabolism; Fatty Liver/etiology/metabolism/prevention & control; Female; Hep G2 Cells; Humans; Lipoproteins, LDL/metabolism; Liver/drug effects/metabolism; Mice; Mice, Inbred C57BL; Mice, Knockout; Pyrazoles/*pharmacology; Pyrimidines/*pharmacology; Reactive Oxygen Species/metabolism; Receptors, LDL/deficiency/genetics; Recombinant Fusion Proteins/metabolism; Signal Transduction/*drug effects; Time Factors; Vascular Calcification/etiology/genetics/metabolism/pathology/*prevention &; control |
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Author: Hjortnaes, J.; New, S. E.; Aikawa, E. |
Title: Visualizing novel concepts of cardiovascular calcification |
Year: 2013 |
Publication: Trends Cardiovasc Med |
Volume: |
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Keywords: OsteoSense |
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Author: Las Heras, F.; DaCosta, R. S.; Pritzker, K. P.; Haroon, N.; Netchev, G.; Tsui, H. W.; Chiu, B.; Erwin, W. M.; Tsui, F. W.; Inman, R. D. |
Title: Aberrant axial mineralization precedes spinal ankylosis: a molecular imaging study in ank/ank mice |
Year: 2011 |
Publication: Arthritis Res Ther |
Volume: 13 |
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Keywords: OsteoSense, Animals; Axis/chemistry/*metabolism/*pathology; *Calcification, Physiologic/genetics; Inflammation/genetics/metabolism/prevention & control; Mice; Mice, Transgenic; Molecular Imaging/*methods; Spondylitis, Ankylosing/diagnosis/*genetics/*metabolism; Time Factors |
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Author: Nakayama, H.; Kawase, T.; Okuda, K.; Wolff, L. F.; Yoshie, H. |
Title: In-vivo near-infrared optical imaging of growing osteosarcoma cell lesions xenografted in mice: dual-channel quantitative evaluation of volume and mineralization |
Year: 2011 |
Publication: Acta Radiol |
Volume: 52 |
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Keywords: OsteoSense,, Animals; Bone Neoplasms/*pathology/physiopathology; Calcification, Physiologic/*physiology; Diphosphonates/diagnostic use; Feasibility Studies; Inositol/analogs & derivatives/diagnostic use; Mice; Mice, Hairless; Osteosarcoma/*pathology/physiopathology; Radiopharmaceuticals/diagnostic use; Spectroscopy, Near-Infrared/*methods; Technetium Tc 99m Medronate/analogs & derivatives/diagnostic use; Transplantation, Heterologous |
