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- 1. Author :
    Elena Aikawa, Matthias Nahrendorf, David Sosnovik, Vincent M. Lok, Farouc A. Jaffer, Masanori Aikawa and Ralph Weissleder
  2. Title :
    Multimodality Molecular Imaging Identifies Proteolytic and Osteogenic Activities in Early Aortic Valve Disease
  3. Type :
    Journal Article
  4. Year :
    2007
  5. Publication :
    Circulation
  6. Products :
    ProSense OsteoSense
  7. Volume :
    115
  8. Issue :
    3
  9. Page Numbers :
    N/A
  10. Research Area :
    Cardiovascular Research
  11. Keywords :
    valves; stenosis; inflammation; atherosclerosis; hypercholesterolemia; imaging; ProSense; OsteoSense
  12. Abstract :
    N/A
  13. URL :
    http://circ.ahajournals.org/cgi/content/full/115/3/377
  14. Call Number :
    PKI @ sarah.piper @
  15. Serial :
    4652
- 1. Author :
    Farouc A. Jaffer; Peter Libby; Ralph Weissleder
  2. Title :
    Molecular Imaging of Cardiovascular Disease
  3. Type :
    Journal Article
  4. Year :
    2007
  5. Publication :
    Circulation
  6. Products :
    ProSense
  7. Volume :
    116
  8. Issue :
    9
  9. Page Numbers :
    N/A
  10. Research Area :
    Cardiovascular Research
  11. Keywords :
    Cardiovascular disease; in vivo imaging; atherosclerosis; magnetic resonance imaging; thrombosis; myocardial infarction; diagnostic imaging; molecular imaging
  12. Abstract :
    No abstract available.
  13. URL :
    http://circ.ahajournals.org/cgi/content/full/116/9/1052
  14. Call Number :
    PKI @ sarah.piper @
  15. Serial :
    4520
- 1. Author :
    Farouc A. Jaffer, Claudio Vinegoni, Michael C. John, Elena Aikawa, Herman K. Gold, Aloke V. Finn, Vasilis Ntziachristos, Peter Libby and Ralph Weissleder
  2. Title :
    Real-Time Catheter Molecular Sensing of Inflammation in Proteolytically Active Atherosclerosis
  3. Type :
    Journal Article
  4. Year :
    2008
  5. Publication :
    Circulation
  6. Products :
    ProSense
  7. Volume :
    118
  8. Issue :
    18
  9. Page Numbers :
    N/A
  10. Research Area :
    Cardiovascular Research
  11. Keywords :
    atherosclerosis; catheters; fluorescence; imaging; inflammation; cathepsins; in vivo imaging; ProSense
  12. Abstract :
    N/A
  13. URL :
    http://circ.ahajournals.org/cgi/content/full/118/18/1802
  14. Call Number :
    PKI @ sarah.piper @
  15. Serial :
    4564
- 1. Author :
    Hidemi Hattori, Kaori Higuchi, Yashiro Nogami, Yoshiko Amano, Masayuki Ishihara and Bonpei Takase
  2. Title :
    A Novel Real-Time Fluorescent Optical Imaging System in Mouse Heart: A Powerful Tool for Studying Coronary Circulation and Cardiac Function
  3. Type :
    Journal Article
  4. Year :
    2009
  5. Publication :
    Circulation: Cardiovascular Imaging
  6. Products :
    AngioSense
  7. Volume :
    2
  8. Issue :
    3
  9. Page Numbers :
    N/A
  10. Research Area :
    Cardiovascular Research
  11. Keywords :
    In vivo imaging; AngioSense
  12. Abstract :
    Extract:
    
    With the advent of tissue regeneration and gene therapy for heart disease, evaluation of coronary circulation and cardiac function in vivo, especially in a disease model, is extremely important. Conventional methods such as microcomputed tomography, high-resolution magnetic resonance angiography, and high-resolution ultrasound have become invaluable tools in cardiovascular research. However, the disadvantages and limitations of these approaches sometimes preclude researchers from conducting important and specific studies on coronary circulation and cardiac function. Therefore, we developed and applied a novel real-time, in vivo fluorescent optical imaging system for use in the mouse cardiovascular system. We report the use of this system for repeatedly assessing coronary circulation, cardiovascular structure, and cardiac function in live mice...
  13. URL :
    http://circimaging.ahajournals.org/content/2/3/277.extract
  14. Call Number :
    PKI @ sarah.piper @
  15. Serial :
    4648
- 1. Author :
    N/A
  2. Title :
    Multimodality Imaging Reveals a Gradual Increase in Matrix Metalloproteinase Activity at Aneurysmal Lesions in Live Fibulin-4 Mice
  3. Type :
    Journal Article
  4. Year :
    2010
  5. Publication :
    Circulation: Cardiovascular Imaging
  6. Products :
    FMT Imaging Systems MMPSense
  7. Volume :
    6
  8. Issue :
    30
  9. Page Numbers :
    N/A
  10. Research Area :
    Cardiovascular Research
  11. Keywords :
    aneurysm; imaging; vasculature; in vivo imaging; FMT; MMPSense
  12. Abstract :
    N/A
  13. URL :
    http://circimaging.ahajournals.org/content/early/2010/06/30/CIRCIMAGING.109.933093.abstract
  14. Call Number :
    PKI @ sarah.piper @
  15. Serial :
    4548
- 1. Author :
    Matthias Nahrendorf; David E. Sosnovik; Peter Waterman; Filip K. Swirski; Ashvin N. Pande; Elena Aikawa; Jose-Luiz Figueiredo; Mikael J. Pittet; Ralph Weissleder
  2. Title :
    Dual Channel Optical Tomographic Imaging of Leukocyte Recruitment and Protease Activity in the Healing Myocardial Infarct
  3. Type :
    Journal Article
  4. Year :
    2007
  5. Publication :
    Circulation Research
  6. Products :
    FMT Imaging Systems AngioSense ProSense
  7. Volume :
    100
  8. Issue :
    8
  9. Page Numbers :
    N/A
  10. Research Area :
    Biology
  11. Keywords :
    molecular imaging; myocardial infarction; inflammation; FMT; fluorescent molecular tomography; in vivo imaging
  12. Abstract :
    N/A
  13. URL :
    http://circres.ahajournals.org/cgi/content/abstract/100/8/1218
  14. Call Number :
    PKI @ sarah.piper @
  15. Serial :
    4482
- 1. Author :
    N/A
  2. Title :
    Whole-Body Optical Imaging in Animal Models to Assess Cancer Development and Progression
  3. Type :
    Journal Article
  4. Year :
    2007
  5. Publication :
    Clinical Cancer Research
  6. Products :
    OsteoSense
  7. Volume :
    13
  8. Issue :
    N/A
  9. Page Numbers :
    N/A
  10. Research Area :
    Cancer
  11. Keywords :
    molecular imaging; cancer; reporter genes; animal models; clinical applications; noninvasive imaging in animal models; animal models of cancer
  12. Abstract :
    Different optical-based imaging models were used to investigate tumor progression and metastasis with particular emphasis on metastasis to bone and bone marrow. We describe how optical imaging can be used to follow important processes in tumor development and treatment response, including angiogenesis, apoptosis, and proteolysis. Finally, we discuss the translation of one optical imaging modality, near-IR fluorescence, from animal validation studies to applications in the clinic related to cancer management.
  13. URL :
    http://clincancerres.aacrjournals.org/content/13/12/3490.full
  14. Call Number :
    PKI @ sarah.piper @
  15. Serial :
    4522
- 1. Author :
    Jesper Hjortnaes; Jonathan Butcher; Jose-Luiz Figueiredo; Mark Riccio; Rainer H. Kohler; Kenneth M. Kozloff;RalphWeissleder ; Elena Aikawa
  2. Title :
    Arterial and aortic valve calcification inversely correlates with osteoporotic bone remodelling: a role for inflammation
  3. Type :
    Journal Article
  4. Year :
    2010
  5. Publication :
    European Heart Journal
  6. Products :
    OsteoSense
  7. Volume :
    31
  8. Issue :
    22
  9. Page Numbers :
    N/A
  10. Research Area :
    Cardiovascular Research
  11. Keywords :
    In vivo imaging; Aortic valve calcification; Atherosclerosis; Inflammation; Bone mineral density; Molecular imaging
  12. Abstract :
    N/A
  13. URL :
    http://eurheartj.oxfordjournals.org/content/early/2010/07/02/eurheartj.ehq237.full.pdf+html
  14. Call Number :
    PKI @ sarah.piper @
  15. Serial :
    4512
- 1. Author :
    Bednar, Bohumil; Zhang, Guo-Jun; Williams Jr, David L; Hargreaves, Richard; Sur, Cyrille
  2. Title :
    Optical molecular imaging in drug discovery and clinical development
  3. Type :
    Journal Article
  4. Year :
    2007
  5. Publication :
    Expert Opinion on Drug Discovery
  6. Products :
    Bioware cell lines
  7. Volume :
    2
  8. Issue :
    1
  9. Page Numbers :
    N/A
  10. Research Area :
    N/A
  11. Keywords :
    Bioware; PC-3M-luc
  12. Abstract :
    N/A
  13. URL :
    http://informahealthcare.com/doi/abs/10.1517/17460441.2.1.65
  14. Call Number :
    PKI @ catherine.lautenschlager @
  15. Serial :
    8973
- 1. Author :
    Jodi Haller; Damon Hyde; Nikolaos Deliolanis; Ruben de Kleine; Mark Niedre; Vasilis Ntziachristos
  2. Title :
    Visualization of pulmonary inflammation using noninvasive fluorescence molecular imaging
  3. Type :
    Journal Article
  4. Year :
    2008
  5. Publication :
    Journal of Applied Physiology
  6. Products :
    ProSense AngioSense
  7. Volume :
    104
  8. Issue :
    3
  9. Page Numbers :
    N/A
  10. Research Area :
    cardiovascular research
  11. Keywords :
    in vivo imaging; small animal imaging; molecular tomography; cysteine proteases
  12. Abstract :
    N/A
  13. URL :
    http://jap.physiology.org/cgi/content/abstract/104/3/795
  14. Call Number :
    PKI @ sarah.piper @
  15. Serial :
    4479